Results 71 to 80 of about 58,715 (251)

INDICATOR OF DYNAMICS OF THE TIME SERIES OF THE NUMBER OF ARRIVALS OF DOMESTIC TOURISTS IN CROATIA IN THE PERIOD BEFORE THE COVID-19 EPIDEMIC

open access: yes, 2021
Hrvatski turizam jedna je od najvažnijih gospodarskih grana Republike Hrvatske. Kada se gleda prema broju noćenja domaćih turista po županijama, Istra je lokacija predvodnica s najviše noćenja, a slijedi ju Splitsko-dalmatinska županija te Kvarner ...
Radmilović, Jasmina
core  

Sustainable Governance of Coastal Areas and Tourism Impact on Waste Production: Panel Analysis of Croatian Municipalities

open access: yes, 2020
The research problem this paper is concerned with is the effect of tourism on solid waste generation in Croatia’s coastal area. We are aware of the fact that this has not been thoroughly addressed, especially considering tourism’s share in ...
Borna Debelić   +5 more
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Do wildfires burn tourism intentions? The case of Portugal [PDF]

open access: yes, 2023
NIPE 01.2023Fire intensity and size incite visitation decrease and recreational losses, relevant tourism variables for European economies. As a result of climate change, this reality is becoming more evident.
Bento-Gonçalves, António   +3 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Ranking different types of tourist accommodation facilities in Serbia using PROMETHEE-GAIA method

open access: yesMенаџмент у хотелијерству и туризму, 2017
This paper presents the ranking of different types of tourist accommodation facilities in Serbia with the highest number of arrivals and overnight stays concerning both domestic and foreign tourists in 2015. PROMETHEE-GAIA method is used for the ranking,
Ivana Ilić
doaj   +4 more sources

Time-series Analysis of the Number of Overnight Guests in the Kyushu-Okinawa Region and Kagoshima Prefecture Districts [PDF]

open access: yes
application/pdfThis paper conducts a time-series analysis of the monthly data on the number of overnight stays in the Kyushu-Okinawa region and in eight districts in Kagoshima Prefecture from January 2007 to December 2019 and from January 2011 to ...
平出, 宜勝
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Development and characteristics of a tourist visit in Slovenia from 1950

open access: yesRevija za Geografijo, 2018
The author points out the main periods of tourist development in Slovenia after 1950, using the data of a tourist visit (the number of tourists and overnight stays, the average length of stay of tourists, their nationality, the seasonality of the tourist
Uroš Horvat
doaj   +1 more source

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