Results 151 to 160 of about 166,225,520 (254)

Decoupling between activation time and steady-state level in input-output responses. [PDF]

PLoS Comput Biol
Ravanelli G, Nam KM, Gunawardena J, Martinez-Corral R.   +3 more
europepmc   +1 more source

Machine‐Learning‐Assisted Impedance Component Analysis Enables Standardizable Surface Protein Analysis of Extracellular Vesicles Using Engineered Nanovesicles

Advanced Science, EarlyView.
This study establishes a universally applicable framework for vesicle surface analysis by combining engineered amyloid‐β‐displaying nanovesicles with machine‐learning‐optimized impedance spectroscopy. Equivalent‐circuit modeling reveals that membrane capacitance correlates with the surface protein states, enabling label‐free quantification of vesicle ...
Jaeyoon Song, Neethu Ramakrishnan, Sehyeon Kim, Huiseop Lee, Youngeun Kwon, Jinsik Kim   +5 more
wiley   +1 more source

Digital Object Identifier (DOI) 10.1007/s00373-004-0568-x Graphs and Combinatorics The Number of Spanning Trees in Kn-Complements

, 2004
or quasi-threshold graphs and derive formulas for their number of spanning trees; for a subgraph H of Kn, the Kn-complement of H is the graph Kn H which is obtained from Kn by removing the edges of H.
Of Quasi-threshold Graphs, Stavros D. Nikolopoulos   +1 more
core  

Defining and cataloging variants in pangenome graphs. [PDF]

Cell Genom
Salehi Nowbandegani P, Zhang S, Hu H, Li H, O'Connor LJ.   +4 more
europepmc   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

Advanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English, Dorothea Böken, Matthew W. Cotton, Matthew R. Cheetham, Johanna S. Jackson, Georg Meisl, John S. H. Danial, Paul M. Matthews, Nurun N. Fancy, David Klenerman   +9 more
wiley   +1 more source

Chromosomal evolution and speciation inferred from chromosome-scale genome assemblies in three Cupressaceae species. [PDF]

DNA Res
Shirasawa K, Aoyagi YB, Mishima K, Hirakawa H, Hirao T.   +4 more
europepmc   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

Latitudinal gradient patterns and driving factors of woody plant sexual systems in forest communities in the Northern Hemisphere. [PDF]

Front Plant Sci
Guo S, Wang Y, Wang L, Fan D, Chen Y, Liu H.   +5 more
europepmc   +1 more source

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source

Strigolactones: From Fundamental Biology to Applications in Tree Breeding. [PDF]

Physiol Plant
Ma Z, Li W, Guo Q, Tibesigwa DG, Meng Q, Wang F.   +5 more
europepmc   +1 more source