Results 101 to 110 of about 170,968 (284)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Technical and Economic Evaluation of Rice Harvesting Methods in Shirvan-Chrdavol Region
Journal of Agricultural Machinery, 2014 Rice is a main food for Iranian people and has an important role in providing food security. Regarding the population growth, increase of rice production and reduction of losses have special importance in prevention of rice import.
M.H Rahmati +3 more
doaj +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Do Tax Cuts Starve the Beast? The Effect of Tax Changes on Government Spending [PDF]
macroeconomics, tax cuts, government spending ...
Christina D. Romer, David H. Romer
core
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Crocodiles - the Singular Beast in the Renaissance Cabinet
, 2017 Stuffed crocodiles often predominated many famous cabinets, hanging in the center of the ceiling. Crocodilians are the largest reptiles and the largest predator that spends time on land.
Zhang, Peter
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Iron Maiden: História, Música e Imagem
Caminhos da História, 2017 Durante a Guerra Fria, em meio aos tumultuados anos da década de 1970, surgiu na Inglaterra a banda de heavy metal Iron Maiden. Apesar do preconceito acerca deste estilo musical, a banda, reconhecida pela qualidade sonora, bem como por letras ...
Fábio Antunes Vieira
doaj
On the Nature of the Beast: Re-Charting Political Geographies of the European Union. Swedish Society for Antropology and Geography, 2006 [PDF]
, 2006 This review paper begins with the premise that since the European Union remains a process of construction with no agreed or pre-designated end-point, its power structure is open to a diverse range of interpretations. Moreover, the apparent novelty of the
Siddaway, James D.
core