Results 121 to 130 of about 13,342,524 (294)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Cognitive control in number processing: new evidence from number compatibility effects in task-switching. [PDF]

open access: yesCogn Process, 2022
Schliephake A   +4 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Magnitude comparison and automaticity in number processing in adolescents with prenatal alcohol exposure: An event-related potentials study. [PDF]

open access: yesAlcohol Clin Exp Res, 2022
Shmueli M   +6 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

IIR array processing based fast adaptive null steering algorithm using shift-invariant subarrays

open access: yes, 2012
This paper presents and investigates a fast adaptive null steering system employing infinite impulse response (IIR) array processing. The new algorithm is of considerable interest in communications where the desired signal is weak compared with the ...
Leng, S., Ser, Wee
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Respiratory rate monitoring by video processing using local motion magnification

open access: yes, 2018
Breathing monitoring by non-contact video processing has been the subject of recent research. This paper presents an advanced video processing algorithm for reliable Respiratory Rate (RR) monitoring based on the analysis of local video variations and a ...
Riccardo Raheli   +11 more
core   +1 more source

Device for number processing

open access: yes, 2011
Пристрій для обробки чисел належить до обчислювальної техніки і може бути використаний для обробки чисел, величина яких задана кількістю імпульсів.Устройство для обработки чисел относится к вычислительной технике и может быть использовано для обработки ...
Мартинюк, Тетяна Борисівна   +8 more
core   +1 more source

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