Results 111 to 120 of about 15,188,620 (312)
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
2016 Gainesville Number Theory Conference
Gathered from the 2016 Gainesville Number Theory Conference honoring Krishna Alladi on his 60th birthday, these proceedings present recent research in number theory.
Andrews, George, Garvan, Frank
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Arbeitsgemeinschaft: Ergodic Theory and Combinatorial Number Theory [PDF]
The aim of this Arbeitsgemeinschaft was to introduce young researchers with various backgrounds to the multifaceted and mutually perpetuating connections between ergodic theory, topological dynamics, combinatorics, and number ...
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Evaluation of the convolution sum involving the sum of divisors function for 22, 44 and 52
The convolution sum, ∑(l,m)∈N02αl+βm=nσ(l)σ(m), $ \begin{array}{} \sum\limits_{{(l\, ,m)\in \mathbb{N}_{0}^{2}}\atop{\alpha \,l+\beta\, m=n}} \sigma(l)\sigma(m), \end{array} $ where αβ = 22, 44, 52, is evaluated for all natural numbers n. Modular forms
Ntienjem Ebénézer
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Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
A REMARK ON THE COUNTABLY Σ−CS RING
Let 𝑅 be a ring such that 𝑅𝑅 = 𝑒1 𝑅 ⊕ · · · ⊕ 𝑒𝑛 𝑅, where each 𝑒𝑖 𝑅 is a uniform right ideal and {𝑒𝑖 | 1 ≤ 𝑖 ≤ 𝑛} is a set of idempotents. We consider the following condition on 𝑅𝑅 : for all 𝑖, 𝑗 ∈ {1, . . . , 𝑛}, the module 𝑒𝑖 𝑅 does not embed in any
Le Van An∗, To Ngoc Le Anh
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Explicit Methods in Number Theory [PDF]
The workshop brought together people attacking key modern problems in number theory via techniques involving concrete or computable descriptions. Here, number theory was interpreted broadly, including algebraic and analytic number theory, Galois theory ...
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Let 𝑅 be a ring such that 𝑅𝑅 = 𝑒1𝑅 ⊕ … ⊕ 𝑒𝑛𝑅 where each 𝑒𝑖𝑅 is a uniform right ideal with finite composition length, and {𝑒𝑖 | 𝑖 = 1, … , 𝑛 } is a set of idempotents. We consider the following condition on 𝑅𝑅: for all distinct 𝑖 and 𝑗, if 𝑙(𝑒𝑖𝑅) < 𝑙 (
Le Van An*, Nguyen Thi Hong
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