Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir+2 more
wiley +1 more source
Graph theory methods for analyzing functional connectivity in multiple spike trains: application to data recorded from the visual cortex of a cat. [PDF]
Masud MS+3 more
europepmc +1 more source
Imperial strategy of cancer cells through mitochondrial transfer
Cangkrama et al. demonstrated that cancer cells donate their mitochondria to fibroblasts through mitochondrial transfer, reprogramming them into ‘MitoCAF’. Likewise, our group has identified mitochondrial transfer from cancer cells to tumor infiltrating lymphocytes, resulting in mitochondrial ‘hijack’ and impaired antitumor immunity.
Takamasa Ishino, Yosuke Togashi
wiley +1 more source
A scoping review protocol for the application of intersectionality in primary care research. [PDF]
Urwin S+6 more
europepmc +1 more source
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir+12 more
wiley +1 more source
Interactions of imidazole with water molecules. [PDF]
Malloum A, Conradie J.
europepmc +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian+6 more
wiley +1 more source
Study on the effect of nursing intervention based on the broaden-and-build theory on the psychosocial adaptability of patients with minimally invasive ablation of liver cancer. [PDF]
Li J+5 more
europepmc +1 more source
The Large Number Hypothesis and Einstein's Theory of Gravitation [PDF]
Yun-Kau Lau
openalex +1 more source