A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
From Ancient Philosophy to Endosymbiotic Theory: The Bacterial Origin and Key Role of Mitochondria in Immune Responses. [PDF]
Mpakosi A+13 more
europepmc +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez+5 more
wiley +1 more source
Perceptual rationality: an evolutionary game theory of perceptually rational decision-making. [PDF]
Salahshour M.
europepmc +1 more source
Exam‐level analysis of lecture capture viewing and student exam performance
This study asks how lecture capture relates to exam performance in biology courses with three noncumulative exams. Mixed‐effects modeling separated between‐students from within‐student effects on exam %. Students who watched more recordings earned higher grades, but viewing spikes above a student's own mean, consistent with cramming, predicted small ...
Kirk Hillsley
wiley +1 more source
Correction: Bessel statistical convergence: New concepts and applications in sequence theory. [PDF]
Ibrahim IS+5 more
europepmc +1 more source
Beyond multiculturalism? Rethinking Japan's "tabunka-kyōsei" through Axel Honneth's theory of recognition. [PDF]
Ishimatsu H.
europepmc +1 more source
Is Schizophrenia a Scapegoat? the Role of Childhood Traumas and Theory of Mind on Crime. [PDF]
Sahabettin C+3 more
europepmc +1 more source
Structure Determination from Single-Molecule X-ray Scattering Images Using Stochastic Gradient Ascent. [PDF]
Schultze S, Luke DR, Grubmüller H.
europepmc +1 more source