Results 81 to 90 of about 1,128,575 (267)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Combinatorics of geometrically distributed random variables: new q-tangent and q-secant numbers
International Journal of Mathematics and Mathematical Sciences, 2000 Up-down permutations are counted by tangent (respectively, secant) numbers. Considering words instead, where the letters are produced by independent geometric distributions, there are several ways of introducing this concept; in the limit they all ...
Helmut Prodinger
doaj +1 more source
The Prouhet Tarry Escott Problem: A Review
Mathematics, 2019 This paper presents a review of the Prouhet Tarry Escott problem. The solutions of the Prouhet Tarry Escott problem are significant because of its numerous applications. Available literature about the present topic has been critically examined. The ideal
Srikanth Raghavendran, Veena Narayanan
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Crystal Constructions in Number Theory [PDF]
, 2019 Weyl group multiple Dirichlet series and metaplectic Whittaker functions can be described in terms of crystal graphs. We present crystals as parameterized by Littelmann patterns and we give a survey of purely combinatorial constructions of prime power coefficients of Weyl group multiple Dirichlet series and metaplectic Whittaker functions using the ...
openaire +3 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Evaluation of the convolution sum involving the sum of divisors function for 22, 44 and 52
Open Mathematics, 2017 The convolution sum, ∑(l,m)∈N02αl+βm=nσ(l)σ(m), $ \begin{array}{} \sum\limits_{{(l\, ,m)\in \mathbb{N}_{0}^{2}}\atop{\alpha \,l+\beta\, m=n}} \sigma(l)\sigma(m), \end{array} $ where αβ = 22, 44, 52, is evaluated for all natural numbers n. Modular forms
Ntienjem Ebénézer
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source