Results 171 to 180 of about 22,884 (263)

Controlled Retrieval Relies on Directed Interactions between Semantic Control Regions and Visual Cortex: MEG Evidence from Oscillatory Dynamics. [PDF]

J Neurosci
Eisenhauer S, Zhang M, Krieger-Redwood K, Aveyard R, Jackson RL, Cornelissen PL, Smallwood J, Jefferies E.   +7 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Orbital angular momentum- and frequency-dependent high-capacity encrypted hologram through multi-dimensional multiplexing acoustic metasurface. [PDF]

Nat Commun
Zhou YQ, Li F, Wu K, Wang W, Liu J, Liang B, Cheng JC.   +6 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Serotype Distribution, Antibiotic Resistance Characteristics, and Virulence Factor Analysis of Group B <i>Streptococcus</i> Isolates in Guangzhou Based on Whole-Genome Sequencing. [PDF]

Infect Drug Resist
Ling Y, Deng Y, Zhang P, Yuan K, Ye L, Zhang X, Chen X, Cui S, Liu J, Zhao Y.   +9 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Ultrafine bubble water irrigation promotes soil particle fragmentation and reduces soil hardness in paddy fields. [PDF]

Sci Rep
Iwama K, Hirooka Y, Izumi Y, Shoji K, Tateishi Y, Watanabe Y, Iijima M.   +6 more
europepmc   +1 more source

Visualised Numerals. [PDF]

The Journal of the Anthropological Institute of Great Britain and Ireland, 1880
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The modulating role of sources of difficulty in interactive matchstick algebra. [PDF]

Front Psychol
Spiridonov V, Erofeeva M, Klowait N, Morozov M, Ardislamov V.   +4 more
europepmc   +1 more source