Results 91 to 100 of about 25,063,531 (316)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Numerical analysis in nonlinear viscoelasticity

open access: yesComputers & Mathematics with Applications, 1980
AbstractThe well-known Volterra integral equation in linear viscoelasticity is treated to characterize the response of nonlinear viscoelastic materials. In this context, a procedure is presented which includes a differential approximation of the time-dependent kernel and an optimization procedure and leads to an optimum selection of certain parameters ...
openaire   +4 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

FIELDS BY CORRELATION ASSEMBLY—A NUMERICAL ANALYSIS TECHNIQUE1,,2 [PDF]

open access: bronze, 1968
Maurice Danard   +2 more
openalex   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

On the Heron's method for approximating the cubic root of a real number

open access: yesJournal of Numerical Analysis and Approximation Theory, 1997
Not available.
Dan Luca, Ion Păvăloiu
doaj  

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