Results 131 to 140 of about 28,044,371 (256)

Numerical analysis of low-frequency electromagnetic field effects from three-phase transformer on coronary stents and cardiac tissues. [PDF]

PLoS One
Tian R, Luo JY, Lu M, Cui JJ.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Numerical Analysis of Cross-Laminated Timber Panels Under Three-Point Bending Using Laminate Theory. [PDF]

Materials (Basel)
Bošanský M, Trcala M.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Numerical Analysis of Laser-Excited SAM-Coated Magnetic Nanoparticles for Electromagnetic Field Enhancement in Optical Gas Sensing. [PDF]

Sensors (Basel)
Kim JH, Choi HW.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Strategies for Navigating Magnetic Microrobots in Neurovascular Networks: A Numerical Analysis. [PDF]

Small Sci
Alves PG, Pinto M, Moreira R, Sivakumaran D, Landers F, Guix M, Nelson BJ, Flouris AD, Pané S, Puigmartí-Luis J, Mayor TS.   +10 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Author Correction: A memetic dynamic coral reef optimisation algorithm for simultaneous training, design, and optimisation of artificial neural networks

Scientific Reports
Francisco Bérchez-Moreno, Antonio M. Durán-Rosal, César Hervás Martínez, Pedro A. Gutiérrez, Juan C. Fernández   +4 more
doaj   +1 more source

Approximate Analytical Approach for Fast Prediction of Microwave Sensor Response: Numerical Analysis and Results. [PDF]

Sensors (Basel)
Cuccaro A, Solimene R, Costanzo S.
europepmc   +1 more source