Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Numerical analysis of low-frequency electromagnetic field effects from three-phase transformer on coronary stents and cardiac tissues. [PDF]
Tian R, Luo JY, Lu M, Cui JJ.
europepmc +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Numerical analysis and performance optimization of a poly(3-hexylthiophene):polynaphthalene-bithiophene heterostructure device using SCAPS-1D simulation. [PDF]
Uddin MN, Chawdhury N.
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Numerical analysis of magnetized Ag-Fe<sub>3</sub>O<sub>4</sub>/VPO hybrid nanofluid flow over a spinning inclined disc with Thompson-Troian slip. [PDF]
Ahmad H +5 more
europepmc +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Integrated Experimental-Numerical Analysis of HTPB Propellant Casting Optimization and Droplet Dynamics. [PDF]
Guo Z, Rossi R, Xue Y, Wu Y, Fu X.
europepmc +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Numerical analysis of flow configuration and channel design for thermoelectric OTEC systems. [PDF]
Wu CI, Tseng WL, Wang BX.
europepmc +1 more source

