Results 271 to 280 of about 27,244,726 (387)

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Numerical analysis of fiber reinforced composite material for structural component application. [PDF]

Heliyon
Amsalu C, Negasa D, Merga A.
europepmc   +1 more source

Cooperative Numerical Analysis of Rapidly Growing Mycobacteria: The Second Report

, 1977
Hajime Saito, Ruth Gordon, I Juhlin, W Käppler, J Kwapinski, C. McDURMONT, S. R. Pattyn, Ernest H. Runyon, J.L. Stanford, I Tárnok, H Tasaka, M Tsukamura, J. G. Weiszfeiler   +12 more
openalex   +1 more source

Numerical Analysis or Numerical Method in Symmetry [PDF]

, 2020
openaire   +2 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Numerical analysis of sodium diffusion in aluminum electrolysis cathode carbon blocks based on a microstructure multi-factor corrected model. [PDF]

PLoS One
Gong C, Xu T, Qi H, Li Y.
europepmc   +1 more source

Phenotypic Description, Numerical Analysis, and Proposal for an Improved Taxonomy and Nomenclature of the Genus Zymomonas Kluyver and van Niel 1936

, 1976
J. De Ley, Jean Swings
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Numerical Analysis of Cavitation Erosion in 316L Steel with CrN PVD Coating. [PDF]

Materials (Basel)
Maurin A.
europepmc   +1 more source

A new numerical calculation method for deconvolution in linear compartment analysis of pharmacokinetics.

, 1977
Hiroshi Kiwada, Kaname Morita, Masahiro Hayashi, Shoji Awazu, Manabu Hanano   +4 more
openalex   +2 more sources