Results 41 to 50 of about 27,671,224 (343)

Polyhedral meshing in numerical analysis of conjugate heat transfer

open access: yes, 2018
Computational methods have been widely applied in conjugate heat transfer analysis. The very first and crucial step in such research is the meshing process which consists in dividing the analysed geometry into numerous small control volumes (cells).
M. Sosnowski   +3 more
semanticscholar   +1 more source

Numerical Large Deviation Analysis of Eigenstate Thermalization Hypothesis

open access: yes, 2018
A plausible mechanism of thermalization in isolated quantum systems is based on the strong version of the eigenstate thermalization hypothesis (ETH), which states that all the energy eigenstates in the microcanonical energy shell have thermal properties.
Iyoda, Eiki   +2 more
core   +1 more source

Numerical simulation of bubble generation in a T-junction [PDF]

open access: yes, 2012
We present a numerical study of the formation of mini-bubbles in a 2D T-junction by means of the fluid dynamics numerical code JADIM. Numerical simulations were carried out for different flow conditions, giving rise to results on the behavior of bubble ...
Arias, Santiago   +2 more
core   +2 more sources

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Convergence Analysis of the Algorithm in "Efficient and Robust Discrete Conformal Equivalence with Boundary" [PDF]

open access: yesarXiv, 2021
In this note we prove that the version of Newton algorithm with line search we used in [2] converges quadratically.
arxiv  

An efficient numerical method for shakedown analysis [PDF]

open access: yes, 2013
The algorithm proposed in [9] for incremental elastoplasticity is extended and applied to shakedown analysis. Using the three field mixed finite element proposed in [22] a series of mathematical programming problems or steps, obtained from the application
Bilotta, A., Garcea, G., Leonetti, L.
core  

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Numerical Methods for Conservation Laws: From Analysis to Algorithms

open access: yes, 2017
The modeling of many problems in the applied sciences and engineering is based on concepts of conservation of mass, momentum and energy, leading to systems of conservation laws.
J. Hesthaven
semanticscholar   +1 more source

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

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