Results 51 to 60 of about 25,063,531 (316)

On a third order iterative method for solving polynomial operator equations

open access: yesJournal of Numerical Analysis and Approximation Theory, 2002
We present a semilocal convergence result for a Newton-type method applied to a polynomial operator equation of degree \(2\). The method consists in fact in evaluating the Jacobian at every two steps, and it has the \(r\)-convergence order at least \(3\).
Emil Cătinaş, Ion Păvăloiu
doaj   +2 more sources

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

Generalized transformations on ratios of Fibonacci and Lucas numbers

open access: yesJournal of Numerical Analysis and Approximation Theory, 1995
Not available.
Ioan Lazăr, Adrian Mureşan
doaj   +2 more sources

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Evaluation of overshooting errors in particle methods for diffusion by biased global random walk

open access: yesJournal of Numerical Analysis and Approximation Theory, 2006
The adjustment of grid steps which guarantees that particles methods yield no numerical diffusion inevitably induces overshooting errors in the solution of the parabolic partial differential equations with space variable coefficients.
Nicolae Suciu, Călin Vamoş
doaj   +2 more sources

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

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