Results 61 to 70 of about 27,671,224 (343)

An Introduction to Numerical Analysis: Bibliography

open access: yes, 2003
Numerical analysis provides the theoretical foundation for the numerical algorithms we rely on to solve a multitude of computational problems in science.
E. Süli, D. Mayers
semanticscholar   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

A memetic dynamic coral reef optimisation algorithm for simultaneous training, design, and optimisation of artificial neural networks

open access: yesScientific Reports
Artificial Neural Networks (ANNs) have been used in a multitude of real-world applications given their predictive capabilities, and algorithms based on gradient descent, such as Backpropagation (BP) and variants, are usually considered for their ...
Francisco Bérchez-Moreno   +4 more
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Numerical Structure Analysis of Regular Hydrogen-Oxygen Detonations [PDF]

open access: yes, 2003
Large-scale numerical simulations have been carried out to analyze the internal wave structure of a regular oscillating low-pressure H2 : O2 : Ar-Chapman-Jouguet detonation in two and three space-dimensions.
Deiterding, Ralf
core  

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

On the multi-decadal oscillation of Atlantic tropical storm activity

open access: yesJournal of Numerical Analysis and Approximation Theory, 2008
Long term Atlantic tropical storm activity is described by the time series of the yearly Accumulated Cyclone Energy (ACE) Index for the time interval 1851-2007.
Constantin Andronache   +2 more
doaj   +2 more sources

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

An iterative method for numerical integration of rational functions [PDF]

open access: yesarXiv, 2008
The rational Landen transformations are used to produce a highly efficient numerical method for the integration of rational functions.
arxiv  

Numerical analysis of corrugated tube flow using RBFNs [PDF]

open access: yes, 2004
This paper reports the application of neural networks for the numerical analysis of steady-state axisymmetric flow through an indefinitely long corrugated tube.
Mai-Duy, Nam, Tanner, Roger I.
core  

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