Results 21 to 30 of about 311,006 (207)

A mathematical model of the gravitational potential of the planet taking into account tidal deformations

open access: yesРоссийский технологический журнал
Objectives. This paper investigates the gravitational potential of a viscoelastic planet moving in the gravitational field of a massive attracting center (star), a satellite and one or more other planets moving in Keplerian elliptical orbits relative to ...
А. V. Shatina, A. S. Borets
doaj   +1 more source

On The Development Of Finite Volume Methods For Computational Solid Mechanics [PDF]

open access: yes, 2007
Since its initial development as a tool for structural analysis around the mid-fifties the Finite Element Method (FEM) has evolved to become the most popular and used method in modern Computational Solid Mechanics.
Idelsohn, Sergio Rodolfo   +1 more
core  

Self-supporting structure design in additive manufacturing through explicit topology optimization

open access: yes, 2017
One of the challenging issues in additive manufacturing (AM) oriented topology optimization is how to design structures that are self-supportive in a manufacture process without introducing additional supporting materials. In the present contribution, it
Du, Zongliang   +5 more
core   +1 more source

New methodology for calculating damage variables evolution in Plastic Damage Model for RC structures [PDF]

open access: yes, 2017
The behavior of reinforced concrete (RC) structures under severe demands, as strong ground motions, is highly complex; this is mainly due to joint operation of concrete and steel, with several coupled failure modes.
Alfarah, Bashar   +2 more
core   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

A phase-field method for modeling cracks with frictional contact

open access: yes, 2019
We introduce a phase-field method for continuous modeling of cracks with frictional contacts. Compared with standard discrete methods for frictional contacts, the phase-field method has two attractive features: (1) it can represent arbitrary crack ...
Choo, Jinhyun, Fei, Fan
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Solid-fluid dynamics of yield-stress fluids

open access: yes, 2014
On the example of two-phase continua experiencing stress induced solid-fluid phase transitions we explore the use of the Euler structure in the formulation of the governing equations.
Grmela, Miroslav   +2 more
core   +1 more source

Linear and non-linear dynamic analyses of sandwich panels with face sheet-tocore debonding [PDF]

open access: yes, 2020
А survey of recent developments in the dynamic analysis of sandwich panels with face sheet-to-core debonding is presented. The finite element method within the ABAQUSTM code is utilized.
Burlayenko, V. N., Sadowski, Tomasz
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

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