Results 221 to 230 of about 2,845,553 (249)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

IFC-HFlowVAE: A self-enhancing generative framework with structural anchoring for imbalanced clinical data augmentation. [PDF]

PLoS One
Yuwen L, Chen S.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Expression patterns of circulating microRNA in confirmed early-onset and late-onset pre-eclampsia cases. [PDF]

Arch Gynecol Obstet
Hoffmann I, Maurer J, Enzensberger C, Stickeler E, Graupner O.   +4 more
europepmc   +1 more source

Reduced-order modeling of nonlinear multiscale industrial systems via sparse regression in latent representations. [PDF]

Sci Rep
Jia D, Zhou X, Li S, Shi H, Li L.
europepmc   +1 more source

Artificial neural network prediction of nonlinear radiative heat transfer and entropy generation in tangent hyperbolic tetra hybrid nanofluid flow over a porous wedge. [PDF]

Discov Nano
Krishnan D, Durgaprasad P.
europepmc   +1 more source

Immature platelet and reticulocyte fractions as dynamic biomarkers of bone marrow activation in dogs and humans: a comprehensive review. [PDF]

Vet Anim Sci
Ahmadi-Hamedani M, Satari K.
europepmc   +1 more source

Congenital and Breed-Associated Vertebral Anomalies in Dogs and Cats: Developmental Anatomy, Genetic Determinants, and Biological Significance. [PDF]

Life (Basel)
Covașă CT, Grădinaru AC.
europepmc   +1 more source

SCD1 Regulates Osteoclast Differentiation by Modulating Arachidonic Acid Metabolism and Mitochondrial Homeostasis. [PDF]

FASEB J
Zhao Y, Wei X, Wu H, Yao C, Zheng Z, Chen W, Feng Z, Huang B, Cai Z, Xue Q, Chen J, Zhao F, Liu J.   +12 more
europepmc   +1 more source