Results 201 to 210 of about 60,674 (269)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

A low-latency deep learning framework for volcanic ash cloud nowcasting using geostationary satellite imagery. [PDF]

Sci Rep
Alves D, Radeta M, Mendonça F, Pereira L, Morgado-Dias F.   +4 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Probabilistic Aseismic Performance Assessment of Rubber-Sand-Concrete Tunnel Linings Considering Spatial Variability of Rock Mass. [PDF]

Materials (Basel)
Li K, Mei X, Li B, Sheng H, Cui Z, Wang Y, Wu H, Wang T.   +7 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Correction for Keogh and Bilal, Combinatorial asymmetric acoustic metamaterials with real-time programmability. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Multicolor interband solitons in microcombs. [PDF]

Light Sci Appl
Ji QX, Hou H, Ge J, Yu Y, Gao M, Jin W, Guo J, Wu L, Liu P, Feshali A, Paniccia M, Bowers J, Vahala K.   +12 more
europepmc   +1 more source

Generalizable, high-throughput image analysis of subcellular structures using dispersion indices. [PDF]

iScience
Martin A, Zhang S, Williamson A, Tingley B, Pickus M, Zurakowski D, Nia HT, Shirihai O, Han X, Grinstaff MW.   +9 more
europepmc   +1 more source

Quadratic few-cycle solitons on chip. [PDF]

Light Sci Appl
Ermolaev AV, Emonin L, Dudley JM.
europepmc   +1 more source