Results 61 to 70 of about 243,906 (306)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Modeling exospheres: analytical and numerical methods with application examples
Exospheres, the tenuous gas environments surrounding planets, planetary satellites, and cometary comae, play a significant role in mediating the interactions of these astronomical bodies with their surrounding space environments.
Valeriy Tenishev +5 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Numerical Computation of Hydrodynamic Wave Impact [PDF]
Extreme waves, their impact loading on floating structures and the resulting dynamic response of these structures have long been subjects that could only be studied with experimental methods.
Kleefsman, K.M. Theresa +5 more
core
The main numerical examples: Climate, assortative mating and CHILD. [PDF]
The main numerical examples: Climate, assortative mating and CHILD.
Bruce C. Petersen (16733847)
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
The basic partial differential equation (PDE) models for supply chain networks with re-entrant nodes and their macroscopic are proposed. However, through numerical examples, the basic continuum models do not perform well for multiple re-entrant systems ...
Fenglan He, Ming Dong, Xiaofeng Shao
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The restoration of constraints in nonholonomic problems - Numerical examples [PDF]
Numerical examples for restoration of constraints in nonholonomic ...
Damoulakis, J. N.
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

