Results 261 to 270 of about 337,061 (308)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Computational and experimental determination of electrochemical standard rate constant from cyclic voltammetry: insights into <i>α</i> + <i>β</i> ≠ 1 systems. [PDF]

RSC Adv
Saad Guermeche R, Affoune AM, Houam S, Atek I, Vautrin-Ul C, Nacef M, Chelaghmia ML, Girault HH, Banks CE, Djaghout I.   +9 more
europepmc   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Function theory on the annulus in the dp-norm. [PDF]

Integr Equ Oper Theory
Agler J, Lykova ZA, Young NJ.
europepmc   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Correction of gas chromatography-mass spectrometry long-term instrumental drift using quality control samples over 155 days. [PDF]

Sci Rep
Yu J, An T, Chen D, Zong S, Bai D, Qi D, Zhang L, Shi J.   +7 more
europepmc   +1 more source

Benchmarking the geographic generalization of deep learning models for precipitation downscaling. [PDF]

Sci Rep
Harder P, Schmidt L, Pelletier F, Ludwig N, Chantry M, Lessig C, Hernandez-Garcia A, Rolnick D.   +7 more
europepmc   +1 more source

A temporal-aware machine learning framework enables microbial community dynamics prediction with personalized precision. [PDF]

Microbiome
Zhang Y, Zhou K, Chen X, Zhang H, Han J, Ning K.   +5 more
europepmc   +1 more source

SPLINE QUASI-INTERPOLATION NUMERICAL METHODS FOR INTEGRO-DIFFERENTIAL EQUATIONS WITH WEAKLY SINGULAR KERNELS

Abdelmonaim Saou, D. Sbibih, M. Tahrichi, D. Barrera   +3 more
openalex   +2 more sources

Parameter calibration of the conceptual rainfall-runoff model based on improved quadratic interpolation optimization. [PDF]

Sci Rep
Zhang J, Zhou Y, Zhou P, Zhu X, Zhang Y, Ning S, Shen J, Jin J.   +7 more
europepmc   +1 more source