Results 201 to 210 of about 3,144,125 (337)

Analysis of thermomechanical stresses in dual compound thick cylinders under asymmetric loads: An analytical and numerical method. [PDF]

Heliyon
Das P, Islam MA, Mondal D.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Author Correction: Supersonic turbulent flow simulation using a scalable parallel modal discontinuous Galerkin numerical method. [PDF]

Sci Rep, 2020
Houba T, Dasgupta A, Gopalakrishnan S, Gosse R, Roy S.   +4 more
europepmc   +1 more source

Numerical Solution of linear first order Singular Systems Using Hes Variational Iteration Method

, 2015
Iosr Journals, S. Sekar, B. Venkatachalam alias Ravikumar   +2 more
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Numerical Analysis on Natural Convection Heat Transfer in a Single Circular Fin-Tube Heat Exchanger (Part 1): Numerical Method. [PDF]

Entropy (Basel), 2020
Lee JH, Shin JH, Chang SM, Min T.
europepmc   +1 more source

Numerical analysis of wetting on textured surfaces by Lattice Boltzmann Method

, 2021
Vincent Neyrand
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

A shallow water numerical method for assessing impacts of hydrodynamics and nutrient transport processes on water quality values of Lake Victoria. [PDF]

Heliyon
Paul S, Reinardy BTI, D Walakira D, Bhattacharya P, Ernstson H, Kalantari Z.   +5 more
europepmc   +1 more source

Contribution to the development of numerical methods using Artificial Neural Network for characterizing the solar potential in Algeria

, 2015
Kahina Dahmani
openalex   +1 more source