Results 71 to 80 of about 520,545 (245)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

The Study of Femoral 3D Reconstruction Process Based on Anatomical Parameters Using a Numerical Method

open access: yesJournal of Biomechanical Science and Engineering, 2008
Computer based three-dimensional (3D) reconstruction technique is widely used in clinical practices and its accuracy is still improving due to introducing of high resolution imaging modalities. Practically, two-dimensional X-ray image might be considered
Moon Kyu LEE   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

An Efficient Numerical Method for Forward Kinematics of Parallel Robots

open access: yesIEEE Access, 2019
Solving the forward kinematics of parallel robots efficiently is important for real-time applications. However, it remains a difficult problem due to its high nonlinearity. This paper combines artificial neural networks and the Global Newton-Raphson with
Qidan Zhu, Zheng Zhang
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

A mathematical model and simulation results of the dynamic system railway vehicle wheel–track with a wheel flat / Dinaminės sistemos „Geležinkelių vagono ratas – kelias“ su rato iščiuoža matematinis modelis ir modeliavimo rezultatai

open access: yesMokslas: Lietuvos Ateitis, 2014
A mathematical model of the system Railway Vehicle Wheel–Track with a wheel flat of a wheelset has been made. The system Railway Vehicle Wheel–Track has been examined on the vertical plane. The mathematical model of the system Railway Vehicle Wheel–Track
Rasa Žygienė   +2 more
doaj   +1 more source

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