Results 71 to 80 of about 520,545 (245)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Computer based three-dimensional (3D) reconstruction technique is widely used in clinical practices and its accuracy is still improving due to introducing of high resolution imaging modalities. Practically, two-dimensional X-ray image might be considered
Moon Kyu LEE +6 more
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
An Efficient Numerical Method for Forward Kinematics of Parallel Robots
Solving the forward kinematics of parallel robots efficiently is important for real-time applications. However, it remains a difficult problem due to its high nonlinearity. This paper combines artificial neural networks and the Global Newton-Raphson with
Qidan Zhu, Zheng Zhang
doaj +1 more source
Modeling of Magnetoelectric Microresonator Using Numerical Method and Simulated Annealing Algorithm. [PDF]
Sadeghi M +3 more
europepmc +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
A mathematical model of the system Railway Vehicle Wheel–Track with a wheel flat of a wheelset has been made. The system Railway Vehicle Wheel–Track has been examined on the vertical plane. The mathematical model of the system Railway Vehicle Wheel–Track
Rasa Žygienė +2 more
doaj +1 more source
Research on slurry diffusion and seepage law in mining overburden fractures based on CFD numerical method. [PDF]
Zhengzheng C +3 more
europepmc +1 more source

