RE: "USING NUMERICAL METHODS TO DESIGN SIMULATIONS: REVISITING THE BALANCING INTERCEPT". [PDF]
Am J Epidemiol, 2022 Zivich PN, Ross RK.
europepmc +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Numerical methods and hypoexponential approximations for gamma distributed delay differential equations. [PDF]
IMA J Appl Math, 2022 Cassidy T +3 more
europepmc +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Frontiers in Built EnvironmentThe present document presents a review on the use of the finite element software package CODE_BRIGHT to simulate reinforced soil structures (RSS).
Aníbal Moncada +4 more
doaj +1 more source
Multi-Layer Fabric Composites Combined with Non-Newtonian Shear Thickening in Ballistic Protection-Hybrid Numerical Methods and Ballistic Tests. [PDF]
Polymers (Basel), 2023 Roszak M +5 more
europepmc +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Should XR Applications Supplement or Replace History Excursions in Education?
International Journal of Serious GamesCultural heritages are important out-of-school learning sites in history lessons, but excursions are associated with high organizational effort for teachers. This article explores whether XR applications can replace or supplement school excursions.
Pascal Mosler +4 more
doaj +1 more source
Numerical methods for the detection of phase defect structures in excitable media. [PDF]
PLoS One, 2022 Kabus D +4 more
europepmc +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source