YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Analysis of eigenvalue condition numbers for a class of randomized numerical methods for singular matrix pencils. [PDF]
Kressner D, Plestenjak B.
europepmc +1 more source
A Program for Numerical Integration of Reaction Rate Laws on the Basis of the Runge-Kutta Method.
Yuji Shinohara +2 more
openalex +2 more sources
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Functionally graded thick-walled tubes analysis by numerical methods. [PDF]
Nastasescu V, Marzavan S.
europepmc +1 more source
The DIOS framework for optimizing infectious disease surveillance: Numerical methods for simulation and multi-objective optimization of surveillance network architectures. [PDF]
Cheng Q +13 more
europepmc +1 more source
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Combined ANFIS and numerical methods to reveal the mass transfer mechanism of ultrasound-enhanced extraction of proteins from millet. [PDF]
Ma YR +5 more
europepmc +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Five Numerical Methods to Assess the Ischemic Risks in Dental Pulp and Neuro-Vascular Bundle Under Orthodontic Movements in Intact Periodontium In Vitro. [PDF]
Moga RA, Olteanu CD, Delean AG.
europepmc +1 more source

