The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Study of Mathematical Models Describing the Thermal Decomposition of Polymers Using Numerical Methods. [PDF]
Zhumanazarova GM +8 more
europepmc +1 more source
Optimization for Software Implementation of Fractional Calculus Numerical Methods in an Embedded System. [PDF]
Matusiak M.
europepmc +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Analysis of eigenvalue condition numbers for a class of randomized numerical methods for singular matrix pencils. [PDF]
Kressner D, Plestenjak B.
europepmc +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Functionally graded thick-walled tubes analysis by numerical methods. [PDF]
Nastasescu V, Marzavan S.
europepmc +1 more source
The DIOS framework for optimizing infectious disease surveillance: Numerical methods for simulation and multi-objective optimization of surveillance network architectures. [PDF]
Cheng Q +13 more
europepmc +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Combined ANFIS and numerical methods to reveal the mass transfer mechanism of ultrasound-enhanced extraction of proteins from millet. [PDF]
Ma YR +5 more
europepmc +1 more source

