Results 71 to 80 of about 1,255 (218)

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Operating characteristics and stability of multiple-fan ventilation systems.

open access: yes, 1995
Augmented-system equations related to a subsystem of a multiple-fan ventilation system are established. It has been found that an augmented system has a unique solution curve and all the possible system solution points are located on the curve at the ...
Lin, Shumin
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Sobre métodos multiescala generalizados para flujo en medios porosos complejos y sus aplicaciones

open access: yes, 2023
ilustraciones, diagramasIn this document, the Generalized Multiscale Finite Element Method (GMsFEM) is studied, which deals with constructing multiscale spectral basis functions designed for high-contrast multiscale problems.
Fernando, Luis   +1 more
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

Analytical Shape Computation of Macromolecules: I. Molecular Area and Volume Through Alpha Shape

open access: yes, 1998
The size and shape of macro-molecules such as proteins and nucleic acids play an important role in their functions. Prior efforts to quantify these properties have been based on various discretization or tessellation procedures involving analytical or ...
Ping Fu   +4 more
core  

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Optimality and Duality for Variational & Bilevel Optimization Problems

open access: yes
Optimization is a fundamental aspect of mathematical modeling and decision-making, playing a crucial role in several areas such as economics, engineering, and operations research.
Dhingra, Vivek
core  

Jeux à champ moyen : méthodes numériques et cas d'agents averses au risque

open access: yes, 2021
Mean field games (abbreviated MFGs) are both a mathematical theory and a modeling tool. Developed in 2006 independently by Jean-Michel Lasry and Pierre-Louis Lions and Minyi Huang, Roland P. Malhamé, and Peter E.
Lavigne, Pierre
core  

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