Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Salp Navigation and Competitive based Parrot Optimizer (SNCPO) for efficient extreme learning machine training and global numerical optimization. [PDF]
Adegboye OR +5 more
europepmc +1 more source
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Numerical optimization of anti resonant hollow core fiber for high sensitivity methane detection. [PDF]
Arman H, Olyaee S, Seifouri M.
europepmc +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Numerical Optimization of Functionally Graded Ti-HAP Material for Tibial Bone Fixation System. [PDF]
Szymkiewicz K.
europepmc +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
AMBWO: An Augmented Multi-Strategy Beluga Whale Optimization for Numerical Optimization Problems. [PDF]
You G, Lu Z, Qiu Z, Cheng H.
europepmc +1 more source
ABSTRACT Background Neurodegeneration with brain iron accumulation (NBIA) comprises a genetically and clinically heterogeneous group of rare neurological disorders characterized particularly by iron accumulation in the basal ganglia. To date, 15 genes have been associated with NBIA.
Seda Susgun +95 more
wiley +1 more source
Numerical optimization of Rb<sub>2</sub>AuScBr<sub>6</sub> and Rb<sub>2</sub>AuScCl<sub>6</sub>-based lead-free perovskite solar cells: device engineering and performance mapping. [PDF]
Al-Amin M +5 more
europepmc +1 more source

