Results 91 to 100 of about 4,989,829 (252)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Differences in arithmetic performance between Chinese and German children are accompanied by differences in processing of symbolic numerical magnitude

open access: yesFrontiers in Psychology, 2016
Symbolic numerical magnitude processing skills are assumed to be fundamental to arithmetic learning. It is, however, still an open question whether better arithmetic skills are reflected in symbolic numerical magnitude processing skills.
Jan Lonnemann   +8 more
doaj   +1 more source

Combining Numerical Analysis and Constraint

open access: yes, 2008
In principle, interval constraints provide tight enclosures for the solutions of several types of numerical problem. These include constrained global optimization and the solution of nonlinear systems of equalities or inequalities.
M. H. Van Emden, Processing By Means
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Functional imaging of numerical processing in adults and 4-y-old children.

open access: yesPLoS Biology, 2006
Adult humans, infants, pre-school children, and non-human animals appear to share a system of approximate numerical processing for non-symbolic stimuli such as arrays of dots or sequences of tones.
Jessica F Cantlon   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Exact Numerical Processing [PDF]

open access: yes, 2003
Paper submitted to Euromicro Symposium on Digital Systems Design (DSD), Belek-Antalya, Turkey, 2003.A model of an exact arithmetic processing is presented.
Mora, Higinio   +2 more
core   +1 more source

Numerical simulation of drying of Pinus pseudostrobus wood with Comsol Multiphysics [PDF]

open access: yes, 2011
In this work, we present the second part of our investigation. In the first part, we have published a semi-empirical model for drying. In this second part, we present the numerical solution of a drying model for Pinus pseudostrobus (Mexican softwood ...
HERNANDEZ-BAUTISTA, Emilio   +11 more
core  

Home - About - Disclaimer - Privacy