Results 71 to 80 of about 770,616 (284)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Approximate numerical radius orthogonality

, 2020
We introduce the notion of approximate numerical radius (Birkhoff) orthogonality and investigate its significant properties. Let $T, S\in \mathbb{B}(\mathscr{H})$ and $\varepsilon \in [0, 1)$. We say that $T$ is approximate numerical radius orthogonal to $S$ and we write $T\perp^{\varepsilon}_ S$ if $$ ^2(T+ S)\geq ^2(T)-2\varepsilon (T) ( S)
Amyari, Maryam, Khibary, Marzieh Moradian   +1 more
openaire   +2 more sources

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Springback Analysis of Flexible Stretch Bending of Multi-Point Roller Dies Process for Y-Profile under Different Process Parameters

Metals, 2021
Springback is a common defect caused by elastic recovery in the plastic forming process, which can cause the formed workpiece to deviate from the target shape.
Chuandong Chen, Jicai Liang, Yi Li, Ce Liang, Wenming Jin   +4 more
doaj   +1 more source

The decomposable numerical radius and numerical radius of a compound matrix

Linear Algebra and its Applications, 1986
Given an \(n\times n\) complex matrix A with singular values \(\alpha_ 1\geq \alpha_ 2\geq...\geq \alpha_ n\) and eigenvalues \(\lambda_ 1,\lambda_ 2,...,\lambda_ n\), where \(| \lambda_ 1| \geq | \lambda_ 2| \geq...\geq | \lambda_ n|\), denote by \(C_ m(A)\) the m-th compound of A(1\(\leq m\leq n)\) and by \(r_ d(C_ m(A))\) and \(r(C_ m(A))\) the ...
openaire   +1 more source

Numerical Radius Inequalities for Hilbert Space Operators [PDF]

Complex Analysis and Operator Theory, 2021
In this work, an improvement of H lder-McCarty inequality is established. Based on that, several refinements of the generalized mixed Schwarz inequality are obtained. Consequently, some new numerical radius inequalities are proved. New inequalities for numerical radius of $n\times n$ matrix of Hilbert space operators are proved as well.
openaire   +3 more sources

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Upper Bounds for the Numerical Radius of Off-Diagonal 2 × 2 Operator Matrices

Mathematics
We establish multiple novel upper estimates for the numerical radius associated with off-diagonal operator matrices defined on a complex Hilbert space H.
Najla Altwaijry, Silvestru Sever Dragomir   +1 more
doaj   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Numerical radius inequalities

, 2022
We introduce some basic theory about numerical range and numerical radius. Basic inequalities for numerical radius which involve one operator and basic inequalities which involve product of two commutative operators are studied. We then introduce more complex numerical radius inequalities for one operator, finding some upper bounds for the nonnegative ...
openaire   +1 more source