Results 81 to 90 of about 419,543 (296)

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Some weighted operator geometric mean inequalities

پژوهش‌های ریاضی, 2017
In this paper, using the extended Holder- -McCarthy inequality, several inequalities involving the α-weighted geometric mean ...
Alemeh Sheikhhosseini, Asma Ilkhanizadeh Manesh, Maryam Khosravi   +2 more
doaj  

Revisiting the Marcus–de Oliveira Conjecture

Mathematics
The Marcus–de Oliveira determinantal conjecture claims that the determinant of the sum of two normal matrices A and B with the prescribed spectra σ(A)={a1,⋯,an} and σ(B)={b1,⋯,bn}, respectively, is contained in the convex hull of the points zσ=∏i=1n(ai ...
Natália Bebiano, João P. da Providência   +1 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Numerical Range of Two Operators in Semi-Inner Product Spaces

Abstract and Applied Analysis, 2012
In this paper, the numerical range for two operators (both linear and nonlinear) have been studied in semi-inner product spaces. The inclusion relations between numerical range, approximate point spectrum, compression spectrum, eigenspectrum, and ...
N. K. Sahu, C. Nahak, S. Nanda
doaj   +1 more source

On some numerical characteristics of operators

Arab Journal of Mathematical Sciences, 2015
We investigate some numerical characteristics of Toeplitz operators including the numerical range, maximal numerical range and maximal Berezin set. Further, we establish an inequality for the Berezin number of an arbitrary operator on the Hardy–Hilbert ...
M. Gürdal, M.T. Garayev, S. Saltan, U. Yamancı   +3 more
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Computing the numerical range of Krein space operators

Open Mathematics, 2014
Consider the Hilbert space (H,〈• , •〉) equipped with the indefinite inner product[u,v]=v*J u,u,v∈ H, where J is an indefinite self-adjoint involution acting on H.
Bebiano Natalia, da Providência J., Nata A., da Providência J.P.   +3 more
doaj   +1 more source

The boundary of the numerical range [PDF]

Glasgow Mathematical Journal, 1981
In [1] it was shown that for a compact normal operator on a Hilbert space the numerical range was the convex hull of the point spectrum. Here it is shown that the same holds for a semi-normal operator whose point spectrum satisfies a density condition (Theorem 1).
openaire   +1 more source