Results 141 to 150 of about 283,918 (290)

Out of Many, One: Toward Rigorous Common Core Standards From the Ground Up [PDF]

open access: yes, 2008
Analyzes high school standards for English in twelve states and math in sixteen states designed for college- and career-readiness. Examines their alignment with the American Diploma Project's benchmarks for common core standards.

core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Estimating Probabilities of Default for Low Default Portfolios

open access: yes, 2005
For credit risk management purposes in general, and for allocation of regulatory capital by banks in particular (Basel II), numerical assessments of the credit-worthiness of borrowers are indispensable.
Pluto, Katja, Tasche, Dirk
core   +1 more source

The Urgency Numeric Rating Scale: Psychometric Evaluation in Adults with Crohn’s Disease

open access: yesAdvances in Therapy
Bowel urgency has recently been recognized as a Crohn's disease (CD) symptom that substantially impacts patients' quality of life. The Urgency NRS is a single-item patient-reported outcome measure assessing bowel urgency severity in the past 24 h (0-10 scale). We aimed to evaluate the psychometric properties of the Urgency Numeric Rating Scale (NRS) in
Dubinsky, M   +8 more
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Effects of daytime variation on pain intensity and analgesic requirement after cesarean section: a retrospective and prospective study

open access: yesAnnals of Medicine
Background This study compared postoperative pain and analgesic requirements in women who underwent cesarean section (CS) in the morning and afternoon.Summary background data It is unclear whether there was difference in postoperative pain intensity and ...
Bin Shu   +7 more
doaj   +1 more source

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