Results 131 to 140 of about 3,840,280 (339)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Existence, Stability, and Data‐Driven Analysis of a Fractional‐Order Avian Influenza Model in Poultry Farms

Engineering Reports
In the present analysis, we consider a chicken disease model in fractional derivatives. The fractional model and its related results are discussed. We present the solution's existence and its uniqueness for the fractional chicken model.
Muhammad Altaf Khan, Mahmoud H. DarAssi, Irfan Ahmad, Ebraheem Alzahrani, Nurulfiza Mat Isa   +4 more
doaj   +1 more source

Trajectory Optimization of Robots With Regenerative Drive Systems: Numerical and Experimental Results [PDF]

, 2019
Poya Khalaf, Hanz Richter
openalex   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Rational Hermite-Padé Approximants vs Padé Approximants. Numerical Results [PDF]

, 2023
Dobrolyubov, Egor O., Nikolay Ikonomov, Leonid Knizhnerman, Sergey Pavlovich Suetin   +3 more
openalex   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Linear Combination of Order Statistics Moments from Log-Extended Exponential Geometric Distribution with Applications to Entropy

Mathematics
Moments of order statistics (OSs) characterize the Weibull–geometric and half-logistic families of distributions, of which the extended exponential–geometric (EEG) distribution is a particular case. The EEG distribution is used to create the log-extended
Fatimah E. Almuhayfith, Mahfooz Alam, Hassan S. Bakouch, Sudeep R. Bapat, Olayan Albalawi   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The Collocation Method in the Numerical Solution of Boundary Value Problems for Neutral Functional Differential Equations. Part I: Convergence Results

, 2015
Stefano Maset
openalex   +2 more sources