Results 111 to 120 of about 548,306 (308)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Numerical solution of the eXtended Pom-Pom model for viscoelastic free surface flows

open access: yes, 2011
In this paper we present a finite difference method for solving two-dimensional viscoelastic unsteady free surface flows governed by the single equation version of the eXtended Pom-Pom (XPP) model. The momentum equations are solved by a projection method
Tome, Murilo F.   +18 more
core   +1 more source

Numerical simulation and design of semiconductor quantum dot-based lasers and amplifiers [PDF]

open access: yes, 2013
Numerical simulation and design of semiconductor quantum dot-based lasers and ...
Xu, Tianhong
core   +1 more source

Dynamical Behavior of a Novel Impulsive Switching Model for HLB with Seasonal Fluctuations

open access: yesComplexity, 2018
This paper studies a new model for Huanglongbing with seasonal fluctuations. Switching coefficients and switching control schemes are considered in this model.
Shujing Gao   +3 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Development of a rotor model for the numerical simulation of helicopter exterior flow-fields

open access: yes, 2004
Includes bibliographical references (leaves 84-85).A numerical methodology is developed to model the effect of a rotor on the surrounding flow-field. The model calculates the time-averaged aerodynamic forces exerted on the air by the fan blades within ...
Hotchkiss, Paul
core  

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Dynamic system simulation on the web [PDF]

open access: yes, 2002
Computer simulation is the discipline of designing a model of an actual or theoretical physical system, executing the model on digital computer, and analysing the execution output.
Mahbub, Khaled
core  

Numerical simulation of flow field in water-pump sump and inlet suction pipe [PDF]

open access: yes, 2010
There are several important considerations in the design of a suction supply sump. It is imperative that the amount of turbulence and entrained air be kept to a minimum.
BOIS, Gérard   +2 more
core   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

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