Results 121 to 130 of about 9,003,743 (375)

New Second-Order Finite Difference Scheme for the Problem of Contaminant in Groundwater Flow

open access: yesJournal of Applied Mathematics, 2012
We develop a new efficient second-order finite difference scheme for two-dimensional problem of contaminant in groundwater flow. Theoretical analysis shows that the scheme is second-order convergence in the L2 norm and is unconditionally stable ...
Quanyong Zhu   +3 more
doaj   +1 more source

Explainable Machine Learning for Scientific Insights and Discoveries

open access: yesIEEE Access, 2020
Machine learning methods have been remarkably successful for a wide range of application areas in the extraction of essential information from data. An exciting and relatively recent development is the uptake of machine learning in the natural sciences ...
Ribana Roscher   +3 more
doaj   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

open access: yesFEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado   +4 more
wiley   +1 more source

Numerical Aerodynamic Simulation (NAS) [PDF]

open access: yes
The history of the Numerical Aerodynamic Simulation Program, which is designed to provide a leading-edge capability to computational aerodynamicists, is traced back to its origin in 1975.
Bailey, F. R.   +2 more
core   +1 more source

Structural and functional characterization of chitinase from carnivorous plant Drosera adelae

open access: yesFEBS Open Bio, EarlyView.
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda   +7 more
wiley   +1 more source

Numerical aerodynamic simulation facility [PDF]

open access: yes
Critical to the advancement of computational aerodynamics capability is the ability to simulate flows about three-dimensional configurations that contain both compressible and viscous effects, including turbulence and flow separation at high Reynolds ...
Bailey, F. R., Hathaway, A. W.
core   +1 more source

Structural and functional analysis of Bacillus sarcosine oxidase and its activity toward cyclic imino acids

open access: yesFEBS Open Bio, EarlyView.
Sarcosine oxidase from Bacillus sp. (SoxB) recognizes l‐proline (l‐Pro), d‐proline (d‐Pro), and l‐thioproline (l‐Tpr) as minor substrates. In this study, we measured their absorption spectra, determined the crystal structures of their enzyme complexes, and performed site‐directed mutagenesis of key residues.
Yuqi Zhang   +5 more
wiley   +1 more source

Computational Hypersonic Aerodynamics with Emphasis on Earth Reentry Capsules

open access: yesINCAS Bulletin, 2016
The temperature in the front region of a hypersonic vehicle nose can be extremely high, for example, reaching approximately 11 000 K at a Mach number of 36 (Apollo reentry) due to the bow shock wave.
Mihai Leonida NICULESCU   +5 more
doaj   +1 more source

A Study of the Shock Sensitivity of Energetic Single Crystals by Large-Scale Ab Initio Molecular Dynamics Simulations

open access: yesNanomaterials, 2019
Understanding the reaction initiation of energetic single crystals under external stimuli is a long-term challenge in the field of high energy density materials.
Lei Zhang, Yi Yu, Meizhen Xiang
doaj   +1 more source

A coupled approximate deconvolution and dynamic mixed scale model for large-eddy simulation

open access: yes, 2007
Large-eddy simulations of incompressible Newtonian fluid flows with approximate deconvolution models based on the van Cittert method are reported. The Legendre spectral element method is used for the spatial discretization to solve the filtered Navier ...
Bouffanais, Roland   +3 more
core   +1 more source

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