Results 101 to 110 of about 8,762,839 (396)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Numerical simulations of ICME–ICME interactions

open access: yesJournal of Space Weather and Space Climate, 2019
We present hydrodynamical simulations of the interaction of Coronal Mass Ejections (CME) in the Interplanetary Medium (IPM). In these events, two consecutive CMEs are launched from the Sun in similar directions within an interval of time of a few hours ...
Niembro Tatiana   +3 more
doaj   +1 more source

Conserving Local Magnetic Helicity in Numerical Simulations

open access: yesThe Astrophysical Journal, 2023
Magnetic helicity is robustly conserved in systems with very large magnetic Reynolds numbers, including most systems of astrophysical interest, and unlike kinetic and magnetic energy, it is not dissipated at small scales.
Yossef Zenati, Ethan T. Vishniac
doaj   +1 more source

Direct Numerical Simulations of Electrophoresis of Charged Colloids [PDF]

open access: yes, 2006
We propose a numerical method to simulate electrohydrodynamic phenomena in charged colloidal dispersions. This method enables us to compute the time evolutions of colloidal particles, ions, and host fluids simultaneously by solving Newton, advection ...
D. C. Henry   +8 more
core   +2 more sources

Incoherent signature of internal tides on sea level in idealized numerical simulations

open access: yes, 2015
The nonpersistent phase relationship between internal tides and astronomical forcings, also known as incoherence, has been identified as a major question in the context of future wide‐swath satellite altimetry.
A. Ponte, P. Klein
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Connecting mean-field theory with dynamo simulations

open access: yesLiving Reviews in Solar Physics
Mean-field dynamo theory, describing the evolution of large-scale magnetic fields, has been the mainstay of theoretical interpretation of magnetism in astrophysical objects such as the Sun for several decades.
Petri J. Käpylä
doaj   +1 more source

Numerical simulations of liquids with amorphous boundary conditions [PDF]

open access: yes, 2010
It has recently become clear that simulations under amorphpous boundary conditions (ABCs) can provide valuable information on the dynamics and thermodynamics of disordered systems with no obvious ordered parameter.
A Cavagna   +10 more
core   +2 more sources

Numerical simulations of super-critical black hole accretion flows in general relativity [PDF]

open access: yes, 2013
A new general relativistic radiation magnetohydrodynamical code KORAL, is described, which employs the M1 scheme to close the radiation moment equations. The code has been successfully verified against a number of tests. Axisymmetric simulations of super-
A. Sa̧dowski   +3 more
semanticscholar   +1 more source

The SXS collaboration catalog of binary black hole simulations [PDF]

open access: yesClassical and quantum gravity, 2019
Accurate models of gravitational waves from merging black holes are necessary for detectors to observe as many events as possible while extracting the maximum science.
M. Boyle   +39 more
semanticscholar   +1 more source

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