Results 191 to 200 of about 185,354 (265)

Model-error estimation and model adaptivity for hyperbolic moment equations in one dimension. [PDF]

Microfluid Nanofluidics
Verbiest R, Koellermeier J.
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Nucci based soliton structures and nonlinear dynamics of the (3+1) dimensional hyperbolic Schrödinger equation. [PDF]

Sci Rep
Shahbaz A, Abbas M, Higazy M, Yousaf MZ, Ogrenmis M, Birhanu A, Hamed YS.   +6 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Going with the flow to solve for symmetry-driven PDE dynamics with physics-informed neural networks. [PDF]

Nat Commun
Kavousanakis ME, Fabiani G, Georgiou AS, Siettos C, Kevrekidis PG, Kevrekidis IG.   +5 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A fullwave model of the nonlinear wave equation with multiple relaxations and relaxing perfectly matched layers for high-order numerical finite difference solutions. [PDF]

Phys Med Biol
Sode M, Pinton G.
europepmc   +1 more source

Volumetric Ablation of Phenolic Resin in Extreme Environments: A Variable-Property Physics-Informed Neural Network Framework. [PDF]

Polymers (Basel)
Du W, Ma T, Song H.
europepmc   +1 more source

Mathematical study on Brinkman type carbon nanofluid flow in channel with bioconvection effect for water treatment applications. [PDF]

Discov Nano
Mohamad AQ, Noranuar WNN, Hashim MR, Zakaria N, Shafie S, Ismail Z, Vieru D, Jamaludin A.   +7 more
europepmc   +1 more source

Optimization of Loading Path for Hydroforming of Asymmetric Curved Tubes Using AMGA. [PDF]

Materials (Basel)
Zheng Z, Tan H, Wu G, Wang F, Tang S, Chen Y, Zhao Y, Yu H, Pan Z.   +8 more
europepmc   +1 more source