Results 51 to 60 of about 7,309,496 (268)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Forward Scatter Radar for Air Surveillance: Characterizing the Target-Receiver Transition from Far-Field to Near-Field Regions

Remote Sensing, 2017
A generalized electromagnetic model is presented in order to predict the response of forward scatter radar (FSR) systems for air-target surveillance applications in both far-field and near-field conditions.
Marta Tecla Falconi, Davide Comite, Alessandro Galli, Debora Pastina, Pierfrancesco Lombardo, Frank Silvio Marzano   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The numerical solution of elliptic and parabolic partial differential equations with boundary singularities [PDF]

, 1976
A general numerical method is described for the solution of linear elliptic and parabolic partial differential equations in the presence of boundary singularities.
Furzeland, RM, Crank, J
core   +2 more sources

Navigation in Restricted Channels Under Environmental Conditions: Fast-Time Simulation by Asynchronous Deep Reinforcement Learning

IEEE Access, 2020
This paper proposes an efficient method, based on reinforcement learning, to be used as ship controller in fast-time simulators within restricted channels.
Jose Amendola, Lucas S. Miura, Anna H. Reali Costa, Fabio G. Cozman, Eduardo Aoun Tannuri   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Numerical Techniques in Loop Quantum Cosmology

Symmetry, Integrability and Geometry: Methods and Applications, 2012
In this article, we review the use of numerical techniques to obtain solutions for the quantum Hamiltonian constraint in loop quantum cosmology (LQC).
David Brizuela, Daniel Cartin, Gaurav Khanna   +2 more
doaj   +1 more source

Digital beam forming methods for variable polarimetric monopulse radar

IET Radar, Sonar & Navigation, 2021
In variable polarimetric monopulse radars, due to the number and types of data channels, the polarisation and angle information of the target in the receiving signals are non‐linearly coupled, which results in incorrect polarisation measurement and ...
Yi Zhang, Zhangfeng Li, Pei Zheng, Houjun Sun   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source