Results 161 to 170 of about 526,880 (335)

Targeting USP1 Potentiates Radiation‐Induced Type I IFN‐Dependent Antitumor Immunity by Enhancing Oligo‐Ubiquitinated SAR1A‐Mediated STING Trafficking and Activation

open access: yesAdvanced Science, EarlyView.
Targeting USP1 is identified as a strategy that significantly enhances type I IFN‐dependent innate immune response within the TME following radiotherapy. Mechanistically, USP1 inhibition facilitates STING trafficking from ER to Golgi by preserving K27‐linked oligo‐ubiquitination of SAR1A, thereby facilitating efficient activation of the dsDNA‐cGAS ...
Weilin Zhou   +15 more
wiley   +1 more source

Does agroecosystem management mitigate historic climate impacts on dryland winter wheat yields?

open access: yesAgronomy Journal, Volume 114, Issue 6, Page 3515-3530, November/December 2022., 2022
Abstract Global studies that quantify climate effects on crop yields using top‐down spatial frameworks are invaluable for assessing generalized effects on world food supplies, yet do not contain the resolution necessary to identify local mediating effects of management. Our objectives were to identify (a) what climate factors have historically affected
Grace L. Miner   +6 more
wiley   +1 more source

How far are today's time-series models from real-world weather forecasting applications? [PDF]

open access: yesarXiv
The development of Time-Series Forecasting (TSF) techniques is often hindered by the lack of comprehensive datasets. This is particularly problematic for time-series weather forecasting, where commonly used datasets suffer from significant limitations such as small size, limited temporal coverage, and sparse spatial distribution.
arxiv  

High‐Conductivity, Self‐Healing, and Adhesive Ionic Hydrogels for Health Monitoring and Human‐Machine Interactions Under Extreme Cold Conditions

open access: yesAdvanced Science, EarlyView.
This study presents an ionic conductive hydrogel (ICH) with excellent conductivity, self‐healing, self‐adhesion, and long‐term stability under extreme cold conditions. It shows significant potential for non‐invasive, continuous health monitoring, conformally adhering to skin without signal crosstalk, enabling real‐time, high‐fidelity signal ...
Fei Han   +12 more
wiley   +1 more source

Yield estimation of summer maize based on multi‐source remote‐sensing data

open access: yesAgronomy Journal, Volume 114, Issue 6, Page 3389-3406, November/December 2022., 2022
Abstract Accurately estimating regional‐scale crop yields is substantial in determining current agricultural production performance and effective agricultural land management. The Yuncheng Basin is an important grain‐producing area in the Shanxi Province. This paper used Sentinel 2A with a spatial resolution of 10 m and MODIS with a temporal resolution
Jingshu Wang   +4 more
wiley   +1 more source

Multi-modal graph neural networks for localized off-grid weather forecasting [PDF]

open access: yesarXiv
Urgent applications like wildfire management and renewable energy generation require precise, localized weather forecasts near the Earth's surface. However, weather forecast products from machine learning or numerical weather models are currently generated on a global regular grid, on which a naive interpolation cannot accurately reflect fine-grained ...
arxiv  

Squamocin Suppresses Tumor Growth through Triggering an Endoplasmic Reticulum Stress‐Associated Degradation of EZH2/MYC Axis

open access: yesAdvanced Science, EarlyView.
Squamocin disrupts mitochondrial respiratory Complex I function, reduces ATP production, and impairs HSP90α function, provoking endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) in multiple cancer tumor models cell lines and in vivo tumor models.
Yin Zhu   +9 more
wiley   +1 more source

Profit‐maximizing potassium fertilizer recommendations for corn and cotton

open access: yesAgronomy Journal, Volume 114, Issue 6, Page 3358-3376, November/December 2022., 2022
Abstract Whereas K fertilization is necessary to maximize corn (Zea mays L.) and cotton (Gossypium hirsutum L.) yields in soils with sub‐optimum K availability, maximizing yield is rarely profit‐maximizing. Estimating the tradeoff between yield and fertilizer cost using current soil‐building and/or yield‐maximizing rate recommendations vs.
Kimberly Oliver   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy