Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Processing speed deficits: A missing link in understanding individual variation in children's interval timing skills? [PDF]
Parr MNDN +7 more
europepmc +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Cognitive bridge between geometric and numerical learning in monkeys. [PDF]
Cantlon JF +3 more
europepmc +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Numerical discrimination in Danionella. [PDF]
Zanon M, Fraser SE, Vallortigara G.
europepmc +1 more source
SodiuM glucose cotrANsporter-2 (SGLT-2) inhibitors in the treatment of type II DiAbetes in Tuscany: utiLizatiOn patteRns, and relatEd clinical use evaluation; the MANDALORE study protocol. [PDF]
Convertino I +7 more
europepmc +1 more source
Correction: Quantum spin models for numerosity perception. [PDF]
Malo JY +3 more
europepmc +1 more source
Auditory perception of biodiversity by human listeners. [PDF]
Grinfeder E +4 more
europepmc +1 more source
Color-selective numerosity adaptation depends on the automatic categorization of colored information. [PDF]
Grasso PA +4 more
europepmc +1 more source

