Results 181 to 190 of about 23,683 (254)

Contrasting effects of different molecular crowding environments on base‐pair opening/closing dynamics of DNA triplex structures

open access: yesThe FEBS Journal, EarlyView.
Base‐pair opening and closing regulate nucleic‐acid structure, stability, and function, but how these motions behave under intracellular molecular crowding remains unclear. Using NMR, we quantified these dynamics in a DNA triplex under two crowder‐reconstituted environments that mimic cellular crowding.
Tomoki Sakamoto   +3 more
wiley   +1 more source

Functional characterization of 42 CK2α de novo variants associated with Okur‐Chung neurodevelopmental syndrome

open access: yesThe FEBS Journal, EarlyView.
Okur‐Chung neurodevelopmental syndrome (OCNDS) is a neurodevelopmental disorder associated with mutations in the gene coding for Protein kinase CK2α. In this work, 42 variants of CK2α associated with OCNDS were characterized in vitro. This included determination of catalytic activity and CK2α/CK2β‐interaction as well as an assessment of evolutionary ...
Alexander Gast   +3 more
wiley   +1 more source

TVB C++: A Fast and Flexible Back-End for The Virtual Brain. [PDF]

open access: yesAdv Sci (Weinh)
Martín I   +7 more
europepmc   +1 more source

Ultrafast python‐integrated single‐entity electrochemical sensor for detecting glycated albumin

open access: yesThe FEBS Journal, EarlyView.
Traditional biosensors suffer from the fact that recognition receptors are immobilised and that they denature on electrodes. Instead here we use receptors freely in solution, minimising surface compression and preserving activity to boost signal efficiency. Python‐driven processing turns the electrochemical response into a rapid, robust readout.
Zihni Onur Uygun
wiley   +1 more source

Assessment and Correction of Non‐Linearity Effects for In Situ Rb‐Sr Geochronology Applied to High 87Rb/86Sr Mica

open access: yesGeostandards and Geoanalytical Research, EarlyView.
Key Points Measurement of 86Sr at count rates < 1500 cps can result in statistical bias. Non‐linear signals in analogue detection mode (e.g., Rb) present a challenge for accurately dating high 87Rb/86Sr mica (> 1000). Accounting for these considerations, high 87Rb/86Sr mica are dated here with accuracies of ∼ 1%.
Duane C. Petts   +5 more
wiley   +1 more source

Spark: modular spiking neural networks. [PDF]

open access: yesFront Artif Intell
Franco M, Gershenson C.
europepmc   +1 more source

Artificial Intelligence in the Detection of Clinically Negotiable Second Mesio‐Buccal Canals in Periapical Images of Maxillary Molars

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim Artificial intelligence (AI) has the potential to aid clinicians in assessing case difficulty in endodontics. The objectives of this study were to develop and validate deep learning models for the detection of clinically negotiable MB2 canals in periapical images of maxillary first and second molars, and to compare the performance of AI ...
Seyed AmirHossein Ourang   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy