Results 81 to 90 of about 141,433 (258)

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

NEW PATIENT ADMISSION MODEL BASED ON INTERPERSONAL RELATIONSHIPS AND ITS IMPACT ON NURSE PERFORMANCE IN HOSPITALS: A SYSTEMATIC

Nurse and Holistic Care
Background: The admission of new patients is a critical phase in inpatient care that shapes first impressions, emotional responses, and perceptions of healthcare quality.
Novia Caecilia Laoli, Nursalam, Ilya Krisnana   +2 more
doaj   +1 more source

A qualitative study of nurse-patient communication and information provision during surgical pre-admission clinics. [PDF]

Health Expect, 2021
Roche D, Jones A.
europepmc   +1 more source

RBM10 Deficiency Promotes Anti‐PD‐1 Resistance in LUAD via STING Alternative Splicing‐Driven CCL7 Signaling and Macrophage Polarization

Advanced Science, EarlyView.
RBM10 deficiency promotes anti‐PD‐1 resistance in lung adenocarcinoma by altering STING alternative splicing, which enhances CCL7 secretion and CCR2‐dependent M2 macrophage polarization. A positive feedback loop via mitochondrial transfer sustains this immunosuppression.
Weitong Gao, Ruqiong Wang, Bo An, Lishuang Qi, Zihan Jing, Xingmei Ren, Yang Zhou, Mingjun Xu, Jiaojiao Li, Jie Liu, Liying Wang, Gang Xu, Rou Li, Dexin Jia, Yan Yu   +14 more
wiley   +1 more source

The relationship of nurse therapeutic communication to inpatient satisfaction

Jurnal Ilmiah Kesehatan Sandi Husada
Introduction: Patient satisfaction is a key indicator of healthcare service quality. One of the most influential factors in determining patient satisfaction is the quality of communication between nurses and patients.
Rasi Rahagia, Dewi Nurhanifah
doaj   +1 more source

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

Advanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng, Wenxia Bu, Fengxu Wang, Yueyuan Jin, Rongzhu Liu, Rui Zhao, Xuehai Wang, Mengna Jiang, Jinping Shen, Xinhang Cheng, Zuming Chen, Li Zhu, Jinlong Li, Zhenzhong Ge, Shichen Miao, Haotian Xu, Xiaoyu Zhou, Dongming Wang, Xinyuan Zhao   +18 more
wiley   +1 more source

Evaluating the therapeutic communication skills of nursing students in the clinical setting: The experiences of students, patients and patients’ relatives

Heliyon
Background: This study aimed to determine the therapeutic communication skills of nursing students, examine their experiences of communication during care, and evaluate the views of patients and their relatives. Methods: This study was designed using the
Neşe Mercan, Sevinç Mersin
doaj   +1 more source

Enabling Nurse-Patient Communication With a Mobile App: Controlled Pretest-Posttest Study With Nurses and Non-English-Speaking Patients. [PDF]

JMIR Nurs, 2021
Silvera-Tawil D, Pocock C, Bradford D, Donnell A, Freyne J, Harrap K, Brinkmann S.   +6 more
europepmc   +1 more source

A Non‐Canonical Role of SMAD4 in Regulating 3D Genome Architecture to Inhibit Lung Squamous Cell Carcinoma Development

Advanced Science, EarlyView.
SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang, Chen Lian, Xinyan Han, Xuhan Zhang, Zihan Wang, Boyu Wang, Taoyu Zhu, Xinrui Lin, Xiaolei Wang, Yaping Xu, Manyu Xiao, Zijin Wang, Junming Li, Silin Chen, Yunze Wang, Yufei Liu, Songsong Li, Zuolin Shen, Xi Lu, Xueqi Han, Yilu Zhou, Mingyang Xiao, Jiayi Ran, Xiaoran Cao, Xinyi Xu, Hugo Sámano‐Sánchez, Alfredo Rodríguez, Lian Wang, Shuifang Chen, Zhanyu Xu, Shirong Zhang, Nuo Yang, Yong Tang, Jian Liu   +33 more
wiley   +1 more source

Hospital-Level Nurse Communication and 30-Day Readmission in United States Acute Care Hospitals: A Cross-Sectional Centers for Medicare and Medicaid Services Hospital Compare Analysis

Nursing Reports
Background: Nurse–patient communication is a nurse-associated, interprofessionally delivered care-process indicator captured by the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS), but its hospital-level association with ...
Pham Minh Son, Huu Thuan Vo, Vu Thi Xim, Thi Kim Ngan Tran, Thi My Nhung Pham, Thi Anh Nguyen   +5 more
doaj   +1 more source