Results 101 to 110 of about 12,875 (317)
Animal Models and Experimental Medicine, EarlyView.In this study, we established a mouse model in which CAG repeats do not undergo microsatellite instability (MSI) across generations. A humanized ATXN2 cDNA with four CAA interruptions within 73 CAG expansions was inserted into the Rosa26 locus of C57BL/6J mice. At the same time, a 23 CAG control mouse model was also generated.
Yao Zhang +9 more
wiley +1 more source
Team-Based Learning Module for Anatomy of the Posterior Upper Limb
MedEdPORTAL, 2015 Introduction This team-based learning (TBL) module was designed for preclinical physician assistant and nurse anesthetist students but is suitable for a variety of medical and health professional students.
William Brooks, Jonathan Isbell
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.We generated two neuron‐specific Cre rat lines, Thy1‐Cre and NeuN‐Cre, using CRISPR/Cas9‐mediated targeted insertion. Both lines were validated for high neural specificity by crossing them with a Cre reporter rat. When bred with an ND1 conditional knockout rat, the two Cre lines produced distinct phenotypic outcomes. These rat lines have been deposited
Keru Li +15 more
wiley +1 more source
PreVALE in OT: Preparing for Various Acutely Lethal Events in the Operating Theater
MedEdPORTAL, 2012 This is a simulation-based, crisis team training course focusing on rarely seen, but acutely life threatening events found specific to the operating theater.
Joseph Turban
doaj +1 more source
Walking clinic in ambulatory surgery: a patient based concept: a Portuguese pioneer project [PDF]
, 2016 Walking Clinic is an innovative, efficient and easily reproducible concept adapted to ambulatory surgery. It consists of a preoperative single day work-up, with a surgeon, an anesthetist and a nurse.
Bate +14 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Chondrocytemetabolic dysfunction plays an important role in osteoarthritis (OA) development during aging and obesity. Protein posttranslational modifications (PTMs) have recently emerged as an important regulator of cellular metabolism. We aim to study one type of PTM, lysine malonylation (MaK), and its regulator sirtuin 5 (Sirt5) in OA ...
Huanhuan Liu +11 more
wiley +1 more source
Mucosal‐associated invariant T cells in rheumatic diseases.
Arthritis &Rheumatology, Accepted Article.Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor (TCR) and restriction by the MHC class I‐related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines. Upon activation, MAIT cells rapidly produce pro‐inflammatory cytokines,
Manon Lesturgie‐Talarek +7 more
wiley +1 more source
Patient Safety in Surgery, 2018 Background Elective surgical case cancellation refers to any elective surgical case that is the list on the day prior to surgery but not operated upon as scheduled.
Melaku Desta +6 more
doaj +1 more source
Factors associated with post-cesarean stillbirth in 12 hospitals in Benin: a cross-sectional
The Pan African Medical Journal, 2016 INTRODUCTION: in spite of free caesarean section applied in Benin since 2009, high rates of stillborn babies continue to be recorded. This study aimed to determine the factors associated with post-caesarean stillborn in Benin.
Virginie Mongbo +6 more
doaj +1 more source