Results 111 to 120 of about 1,572,002 (336)

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Supporting Clinicians after Adverse Events: Development of a Clinician Peer Support Program

Journal of patient safety, 2018
Background Many healthcare organizations have developed processes for supporting the emotional needs of patients and their families after medical errors or adverse events.
M. Lane, Brianne M. Newman, M. Taylor, Meg O’Neill, C. Ghetti, Robin M Woltman, A. Waterman   +6 more
semanticscholar   +1 more source

Telephone triage for management of same-day consultation requests in general practice (the ESTEEM trial): a cluster-randomised controlled trial and cost-consequence analysis [PDF]

, 2014
BACKGROUND: Telephone triage is increasingly used to manage workload in primary care; however, supporting evidence for this approach is scarce. We aimed to assess the effectiveness and cost consequences of general practitioner-(GP)-led and nurse-led ...
Lattimer, V, Richards, David A, Richards, David, Richards, SH, Warren, Fiona C., Kandiyali, R, Kandiyali, Rebecca, Campbell, John L, Green, C, Salisbury, Chris, Varley, A, Richards, DA, Murdoch, J, Taylor, RS, Varley, Anna, Green, Colin, Warren, Fiona C, Warren, FC, Britten, N, Britten, Nicky, Richards, Dave A., Chaplin, Katherine, Holt, TA, Taylor, Rod S, Richards, Suzanne H, Murdoch, Jamie, Bowyer, V., Roscoe, J, Fletcher, Emily, Richards, David A., Richards, Suzanne H., Chaplin, K, Campbell, John, Holt, Tim A, Bowyer, Vicky, Fletcher, E, Taylor, Rod, Lattimer, Valerie Ann, Lattimer, Valerie, Taylor, Rod S., Campbell, JL, Bowyer, V, Campbell, John L., Holt, Tim A., Salisbury, C, Calitri, R, Calitri, Raff, Roscoe, Julia, Kandiyali, Rebecca S   +48 more
core   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

From Label‐Free Multiphoton Imaging to Pathological Reports: A Vision‐Language Breast Cancer Margin Pathological Diagnosis System

Advanced Science, EarlyView.
MarginPath is a novel vision‐language system that automates breast cancer margin assessment using a single label‐free multiphoton microscopy image. By integrating tumor‐associated collagen signatures with virtual H&E imaging, it generates accurate margin heatmaps and comprehensive diagnostic reports.
Shu Wang, Jingze Su, Xiahui Han, Deyong Kang, Xiao Zhang, Fei Xu, Changzu Liu, Junlin Pan, Xingfu Wang, Qiaohui Zhan, Aimin Wang, Feng Huang, Heping Cheng, Wenxi Liu, Ruolan Lin, Jianxin Chen   +15 more
wiley   +1 more source

Bilateral SERS‐Microneedle Patch for Co‐Diagnosis of Diabetes Mellitus and Tuberculosis Comorbidity

Advanced Science, EarlyView.
Our study introduced a U@mP@Au‐mediated bilateral SERS‐microneedle patch for analyzing glucose levels from ISF and sensitively detecting TB biomarkers from sputum, respectively. This integrated dual‐analyte detecting platform can be used for co‐diagnosis of diabetes mellitus (DM) and tuberculosis (TB) comorbidity, which was demonstrated in ex vivo ...
Xueqin Huang, Lingzhi Chen, Jing Xu, Jiaqi Yu, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Lang Rao, Jierong Chen, Junxia Zheng, Haibo Zhou   +12 more
wiley   +1 more source

Cognition and expectation about the role of nurse practitioner among hematology clinicians:a qualitative study

Huli yanjiu
ObjectiveTo explore the cognition and expectation about the role of nurse practitioner among hematology clinicians,and to provide reference for post setting and practice content design of nurse practitioner in hematology department.MethodsBased on the ...
LIU Lingyu, YAN Tingting, LI Xiaobin, GUO Jinli, GUO Jianli, WEI Wei, LI Mingzi   +6 more
doaj  

Certification in Nursing Education: Implications for Nurse Practitioner Faculty

, 2012
Faculty selected to teach in programs that educate nurse practitioners (NPs) are often excellent clinicians.  However, nurse practitioner faculties often have knowledge deficits in areas related to educational pedagogy, theory, and instructional and ...
Waldrop, Julee B., Blackwell, Christopher W.   +1 more
core  

Pancreatic Atrophy: A Narrative Review and Surgical Interpretation

Annals of Gastroenterological Surgery, EarlyView.
Pancreatic parenchymal atrophy pattern and intraoperative margin assessment guide surgical strategy. ABSTRACT Despite recent advances in multimodal management, pancreatic ductal adenocarcinoma remains a fatal malignancy. Early detection of indirect findings of pancreatic ductal adenocarcinoma is essential to improve treatment outcomes, drawing ...
Rika Fujino, Ken‐ichi Okada, Yohei Masugi, Eisuke Iwasaki, Masaki Mori   +4 more
wiley   +1 more source