Results 141 to 150 of about 924 (214)

Genetic testing practices across European epilepsy centers: An ERN EpiCARE survey

Epilepsia Open, EarlyView.
Abstract Objective Genetic testing plays an increasing role in the diagnostic pathway for rare and complex epilepsies. However, significant heterogeneity persists in access, implementation, and interpretation across Europe. This study aimed to assess genetic testing practices, accessibility, and challenges across expert epilepsy centers within the ...
Sébile Tchaicha, Johanna Van Hulle, Eva Brilstra, Andreas Brunklaus, Gaetano Cantalupo, Martin Geroldinger, Amy McTague, Reetta Kälviäinen, Eulalia Turón‐Viñas, Alexis Arzimanoglou, Rikke S. Møller, Rima Nabbout   +11 more
wiley   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

A primary care‐led school‐centered model for epilepsy detection and care among children in India

Epilepsia Open, EarlyView.
Abstract Objective We evaluated whether a primary care‐led, school‐centered epilepsy detection model, delivered through India's national school health program, Rashtriya Bal Swasthya Karyakram (RBSK), could improve childhood epilepsy detection and the knowledge, attitudes, and practices (KAP) of teachers and primary healthcare providers.
Sulena Sulena, Gagandeep Singh, Akanksha Nagar, Preeti Padda   +3 more
wiley   +1 more source

Fenfluramine in Rett syndrome: A multidimensional clinical study

Epilepsia Open, EarlyView.
Abstract Objective Rett syndrome (RTT) is a severe neurodevelopmental disorder frequently associated with drug‐resistant epilepsy, autonomic dysfunction, respiratory abnormalities, sleep disturbances, and behavioral impairment. Fenfluramine has shown efficacy in developmental and epileptic encephalopathies and may provide broader therapeutic benefits ...
Elena Gonzalez‐Alguacil, Nuria Lamagrande Casanova, Manuel Luján Bonete, David Mansilla Lozano, Juan José García Peñas, María Ballará Petitbó, Rocío Trincado Lamuño, Verónica Cantarín‐Extremera, Raquel Díaz Conejo, César Rodríguez Sánchez, Adrián García Ron, Víctor Soto Insuga   +11 more
wiley   +1 more source

Severe and Enduring Eating Disorders: A Qualitative Study of Patients' Experiences and Perceived Treatment Needs

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Approximately 25% of individuals with eating disorders develop severe and enduring eating disorders (SEEDs); yet effective treatments remain limited. This study explored lived experiences of SEEDs, focussing on past treatments, as well as current needs and hopes. Method Twenty participants with eating disorders of ≥ 7 years and prior
Emilia Kotilahti, Anu Ruusunen, Katarina Lindstedt, Rasmus Isomaa   +3 more
wiley   +1 more source

Transition From Child to Adult Eating Disorder Services: A Qualitative Meta‐Aggregation

European Eating Disorders Review, EarlyView.
ABSTRACT Background Some young people with eating disorders (EDs) require transfer from paediatric to adult services, which can be difficult and distressing. While most research on this topic is qualitative, no qualitative focused synthesis yet exists.
Amelia Austin, Manya Singh, Sela Scott, Maria Nicula, Andrea Krishnapillai, Jayden Lee, Cheryl Webb, Ana Cláudia Vieira de Almeida, Mehar Sesan, Heidi Vander Steen, Julia Hews‐Girard, Christopher J. Mushquash, Melissa Kimber, Jennifer Couturier, Gina Dimitropoulos   +14 more
wiley   +1 more source

Healthcare Professionals’ Experiences of Barriers and Facilitators to ARFID Identification, Diagnosis and Treatment: A Rapid Review

European Eating Disorders Review, EarlyView.
ABSTRACT Objectives Despite increasing evidence of the physical and psychosocial impairments associated with Avoidant/Restrictive Food Intake Disorder (ARFID), there are currently no national guidelines for its assessment and treatment. In the absence of such guidance, it is crucial to understand the experiences of healthcare professionals (HCPs ...
Sandra‐Eve Bamigbade, Freya Cooper, Amanda Ludlow   +2 more
wiley   +1 more source

Calorie‐Free Menus as a Potential Mitigation Strategy for Mandatory Calorie Labelling: Evidence From People With Disordered Eating in England

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Since the introduction of mandatory out‐of‐home calorie labelling in England, concerns have been raised about potential negative impacts on people with disordered eating. To mitigate these concerns, food outlets can provide calorie‐free menus on request.
Nora Trompeter, Abinaya Nadarajah, Fiona Duffy, Helen Sharpe, Ellen Maloney, Ulrike Schmidt, Lucy Serpell, Dasha Nicholls, Tom Jewell   +8 more
wiley   +1 more source

‘They Should Understand That the Anorexia Drives me to do Anything’: Exploring How Individuals With Anorexia Nervosa Make Sense of the Experience of Medical Admissions

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a complex disorder associated with significant morbidity and mortality. Some people with AN require medical admissions to manage physical complications. Currently, little is known about how these medical admissions are experienced, despite an increase in the number of individuals being hospitalised.
Hannah Webb, Penny Neild, Vanessa Lawrence, Ulrike Schmidt, Maria Griffiths   +4 more
wiley   +1 more source

Eating Disorder Clinician Views About the Impact of Out‐of‐Home Calorie Labelling on Their Patients: A Qualitative Interview Study

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Accumulating evidence suggests that people with eating disorders experience mainly negative impacts of out‐of‐home calorie labelling. This study explored eating disorder clinician perspectives on how such labels affect individuals with eating disorders, and their views on implementation of this policy.
Abinaya Nadarajah, Imogen Peebles, Fiona Duffy, Nora Trompeter, Ellen Maloney, Dasha Nicholls, Ulrike Schmidt, Lucy Serpell, Helen Sharpe, Tom Jewell   +9 more
wiley   +1 more source