Results 181 to 190 of about 104,711 (263)

Expanding the electroclinical spectrum of TANC2‐related disorders: Lennox–Gastaut syndrome and related developmental epileptic phenotypes

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Neurodevelopmental disorders (NDDs) and epilepsy are often associated. Increasing evidence highlights a pivotal role for pathogenic variants in genes encoding synaptic scaffolding proteins. Within this group, TANC2 has recently been implicated in intellectual developmental disorder with autistic features and language delay, with or ...
Lorenzo Perilli   +12 more
wiley   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

open access: yesEpilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar   +4 more
wiley   +1 more source

Severe and Enduring Eating Disorders: A Qualitative Study of Patients' Experiences and Perceived Treatment Needs

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective Approximately 25% of individuals with eating disorders develop severe and enduring eating disorders (SEEDs); yet effective treatments remain limited. This study explored lived experiences of SEEDs, focussing on past treatments, as well as current needs and hopes. Method Twenty participants with eating disorders of ≥ 7 years and prior
Emilia Kotilahti   +3 more
wiley   +1 more source

Virtual Care and Health Care Access: Pragmatic Evaluation of Implementation, Acceptance, and Use in General Practice and Aged Care Homes. [PDF]

open access: yesJ Med Internet Res
Bamgboje-Ayodele A   +8 more
europepmc   +1 more source

Transition From Child to Adult Eating Disorder Services: A Qualitative Meta‐Aggregation

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Background Some young people with eating disorders (EDs) require transfer from paediatric to adult services, which can be difficult and distressing. While most research on this topic is qualitative, no qualitative focused synthesis yet exists.
Amelia Austin   +14 more
wiley   +1 more source

Pathways to the Quintuple Aim: The Role of Advanced Practice Clinicians in Valvular Heart Disease. [PDF]

open access: yesJACC Adv
Cantey C   +7 more
europepmc   +1 more source

Healthcare Professionals’ Experiences of Barriers and Facilitators to ARFID Identification, Diagnosis and Treatment: A Rapid Review

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objectives Despite increasing evidence of the physical and psychosocial impairments associated with Avoidant/Restrictive Food Intake Disorder (ARFID), there are currently no national guidelines for its assessment and treatment. In the absence of such guidance, it is crucial to understand the experiences of healthcare professionals (HCPs ...
Sandra‐Eve Bamigbade   +2 more
wiley   +1 more source

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