Results 281 to 290 of about 6,332,549 (358)
Organoid Modeling of Mouse Anterior Tongue Epithelium Reveals Regional and Cellular Identities
Advanced Science, EarlyView.The tongue's anterior epithelium is maintained by region‐specific stem/progenitor cells, yet in vitro models are limited. Long‐term expanding organoids are developed from adult mouse anterior tongue that retain region‐specific identity, cellular diversity, and gene regulatory features. These organoids differentiate into keratinocytes, Merkel‐like cells,
Seok‐Young Kim +12 more
wiley +1 more source
Advanced Science, EarlyView.Spatial transcriptomic analysis of Anaplastic thyroid carcinoma (ATC)‐differentiated thyroid carcinoma (DTC) coexisting tumors reveals that coexisting DTC regions with ATC‐like genomic alterations undergo sequential transcriptomic reprogramming and immune microenvironment remodeling, ultimately evolving into a full ATC pathological phenotype.
Kang Ning +19 more
wiley +1 more source
Advanced Science, EarlyView.This article examines the central role of RIPK1 in the pathogenesis of sepsis‐induced lung injury. It elucidates how RIPK1 initiates an inflammatory cascade by activating JAK1‐STAT3 signaling, leading to CXCL1‐mediated neutrophil infiltration. Importantly, it demonstrates that pharmacological inhibition of RIPK1 effectively attenuates inflammation and ...
Hao Sun +15 more
wiley +1 more source
Nurse education and understanding related to domestic violence and abuse against women: An integrative review of the literature. [PDF]
Nurs Open, 2018 Alshammari KF +2 more
europepmc +1 more source
Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication
Advanced Science, EarlyView.EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu +12 more
wiley +1 more source
A Study Examining the Influence of Proximity to Nurse Education Resources on Quality of Care Outcomes in Nursing Homes. [PDF]
Inquiry, 2018 Haun CN +3 more
europepmc +1 more source
Advanced Science, EarlyView.Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin +15 more
wiley +1 more source