Results 71 to 80 of about 90,103 (259)
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Frontiers in Health ServicesBackgroundSpecialist nurses represent an important pathway through which registered nurses transition toward advanced practice nurse roles, and their development and clinical practice are essential for addressing contemporary healthcare challenges ...
MengJuan Jing +5 more
doaj +1 more source
Advanced Nursing Practice in New Zealand: 1998
Nursing Praxis in Aotearoa New Zealand, 1998 In the last decade, change in the health sector has often seemed to deny and thwart the professionalism and expertise of nurses. However, in the first half of 1998, a number of positive initiatives have come to fruition, which support the development of
Susan Jacobs
doaj +1 more source
Cirugía Cardiovascular, 2019 Durable ventricular assist devices (VAD), despite being a standard therapy for adults in end-stage heart failure, are not so extended among the paediatric population for some reasons.
Ana Redondo +4 more
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Huli yanjiu, 2018 This article reviewed the status quo of certification，recognition，and practice on pain management nurses(PMN) and advanced practicepain management nurse (APPMN) in the United States and pain specialist nurse in China.It pointed out that the relevant ...
Chen Jiajia +3 more
doaj
Mothers’ Preventive Measures of COVID-19 among Their Primary School Children [PDF]
Egyptian Journal of Health CareBackground: In epidemics such as COVID-19, major changes need to be made to the population's behavior to prevent infection and stop disease transmission.
Eman Ibrahim Mohamed Eltantawy +2 more
doaj +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
From the field: Educating DR patients on gaining better diabetes control
Community Eye Health Journal, 2015 As part of the Vision 2020 Links Programme, a team from the Diabetes Eye Screening Department at Homerton University Hospital in London, UK visited the University Hospital of West Indies (UHWI) in Kingston, Jamaica in June 2015.
Zhara Gregory
doaj
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source