Results 151 to 160 of about 661,532 (288)

P66 A year of living safely: 12 months of DAA treatment in Canberra's prison system

open access: yesJournal of Virus Eradication, 2017
J. Wenke, R. Evan, B. Harkness
doaj   +1 more source

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

open access: yesAdvanced Science, EarlyView.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon   +6 more
wiley   +1 more source

Scaling up pediatric nurse specialist education in Ghana - a longitudinal, mixed methods evaluation. [PDF]

open access: yesBMC Nurs, 2021
Salehi R   +7 more
europepmc   +1 more source

Gαi1/3 Are Essential for BMP2‐Induced Osteogenesis by Bridging BMP Receptors to the Gab1 Signaling Complex

open access: yesAdvanced Science, EarlyView.
The Gαi1/3 protein is a crucial connecting protein closely related to the signal transduction process of bone formation‐related cytokines such as BMP2. Gαi1/3 mediates downstream signaling pathways such as Smads and MAPK by binding to adaptor proteins like Gab1, thereby promoting the osteogenic effect of BMSCs.
Huajian Shan   +10 more
wiley   +1 more source

The Feasibility of the Role of Clinical Nurse Specialist in Taiwan: The Delphi Technique

open access: yes, 2017
[[abstract]]本研究之目的在探討護理界及醫界對發展專科護理師角色之共識,以作爲未來國內發展專科護理師之參攷,其主要重點如下:(1)探討發展專科護理師的可行性,(2)訂立專科護理師遴選標准,(3)制定專科護理師訓練內容,(4)規劃專科護理師之角色功能範圍,(5)探討專科護理師之資格維持辦法,(6)建議專科護理師之甄審機構,(7)建議專科護理師合宜分科。本研究採德爾菲研究法(Delphi technique)。共進行三回合問卷審視後,專家間已産生共識 ...
盧美秀;林佳靜;林秋芬;廖美南;張丹蓉
core  

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

open access: yesAdvanced Science, EarlyView.
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu   +4 more
wiley   +1 more source

Unveiling the Taxonomic Diversity and Unprecedented Biosynthetic Treasure of the Phylum Myxococcota

open access: yesAdvanced Science, EarlyView.
Natural products remain vital sources of therapeutics, and the phylum Myxococcota constitutes an especially rich reservoir for them. Based on decades of microbiological efforts, we present 154 new Myxococcota genomes and revise taxonomy quadrupling the number of families and genera.
Amay Ajaykumar Agrawal   +25 more
wiley   +1 more source

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