Results 121 to 130 of about 661,990 (286)

Operational mechanism of clinical nurse specialist outpatient clinics for gastric cancer in the UK and its implications for China

open access: yesHuli yanjiu
ObjectiveTo explore the operational mechanism of the clinical nurse specialist(CNS) outpatient model for gastric cancer in the UK and to analyze its implications for the development of the gastric cancer nursing service system in China.MethodsA framework
JIANG Yi   +3 more
doaj  

A Glucose Metabolism‐Modulatory Nanobiohybrid Vaccine Platform Promotes Anti‐Tumor Immunity by Orchestrating Autophagy‐Dependent Cross‐Presentation and H2S‐Enhanced NLRP3 Inflammasome Signaling

open access: yesAdvanced Science, EarlyView.
A nanobiohybrid vaccine was designed by constructing a hydrogen‐bonded organic framework coencapsulated with glucose oxidase (GOx) and tumor antigens. This nanobiohybrid vaccine executed a GOx‐catalyzed enzyme reaction that disrupted glucose metabolism and induced redox imbalance in dendritic cells, leading to autophagy‐dependent antigen cross ...
Weidong Wang   +5 more
wiley   +1 more source

Reversing Temozolomide Resistance in Glioblastoma Based on Cuproptosis‐Mediated Positive Feedback Loop

open access: yesAdvanced Science, EarlyView.
To effectively reverse TMZ resistance, this work proposes a cuproptosis‐mediated positive feedback loop that integrates mitochondrial dysfunction, ATP depletion, AMPK‐p53 signaling, and glycolytic inhibition, ultimately amplifying cell death. This cuproptosis‐mediated feedback loop simultaneously disrupts multiple resistance pathways in GBM, including ...
Wenjie Feng   +9 more
wiley   +1 more source

ATTITUDES OF SPECIALIST NURSES TOWARDS DEATH: PARTICULARITIES OF SPECIALIST NURSES IN REHABILITATION NURSING

open access: yesRevista Portuguesa de Enfermagem de Reabilitação, 2020
Objetivo: analisar as diferenças no perfil de atitudes face à morte entre enfermeiros especialistas em enfermagem de reabilitação e enfermeiros especialistas em outras áreas. Método: estudo comparativo, quantitativo, transversal, com participação de 223 enfermeiros especialistas de um hospital do norte de Portugal. Como instrumento de colheita de dados
Cardoso, Maria Filomena Passos Teixeira   +3 more
openaire   +2 more sources

Guiding the Clinical Nurse Specialist role in oncology within Princess Margaret Cancer Centre. [PDF]

open access: yesCan Oncol Nurs J, 2022
Cheung V   +5 more
europepmc   +1 more source

Immediate Growth Control in Response to Boiling Histotripsy is Prognostic for Intratumoral Immune Activation

open access: yesAdvanced Science, EarlyView.
Boiling Histrotripsy (BH), a mechanical form of focused ultrasound (FUS), allows for non‐invasive and non‐ionizing tissue destruction. Utilizing a BH treatment protocol that yielded bifurcating primary tumor growth responses, we found that immediate BH‐induced tumor growth control identifies tumors with acute reductions in antigen‐presenting cells (APC)
Lydia E. Kitelinger   +8 more
wiley   +1 more source

AUSPRAC : The Nurse Practitioner Research Toolkit [PDF]

open access: yes, 2010
Chapter 1: Introduction\ud \ud Overview and background\ud \ud Chapter 2: Conducting clinical audit of nurse practitioner practice \ud \ud The nature and purpose of clinical audit--\ud Data collection tools for clinical audit--\ud References and readings ...
Gardner, Glenn E.   +3 more
core   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

open access: yesAdvanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong   +14 more
wiley   +1 more source

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